| Purpose:This paper aims to explore and discuss the safety and efficiency of Baoyuan Decoction and Dumai Ironing Method while elderly that suffer from stable angina pectoris(qi deficiency syndrome)of coronary heart disease being the treated audiencea and provide clinical evidence for the prevention and treatment of stable angina pectoris of elderly coronary heart disease with traditional Chinese medicine.Material and method:The clinical trial project passed the ethics review of the ethics committee of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,number(2017022CS(KT)-010-01).In the case of a limited period of time from Sep.2018 to Dec.2020,the elderly-aged patients in the outpatient department of geriatrics of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine who belongs to the age segment of 60 and above,while being diagnosed as Qi-deficiency syndrome and suffering from stable angina pectoris of coronary heart disease,have been divided into Dumai Ironing group(26 cases),Baoyuan Decoction group(26 cases)and control group(25 cases).During a four-week course of treatment,while providing a combination of Dumai Ironing therapy with western medicine conventional treatment to the Dumai Ironing group,we treated the Baoyuan Decoction group with Baoyuan Decoction and conventional western medicine,and the control group with Western medicine conventional treatment.The changes that taken place to the safety indicators of the three groups of samples,from their liver and kidney function,electrocardiogram,and Seattle angina pectoris assessment,to the blood lipid levels(TC,TG,LDL-C,HDL-C),quality of life SF-12 score,and TCM body mass scale scores are to be observed before and after the four-week course of treatment.SPSS22.0 is applied for processing and analyzing the obtained data.Results:1.A total of 106 people were screened in this clinical trial,and 77 people were enrolled in the group.A patient in the Baoyuan Decoction group reported experiencing orbital pain after taking the drug,which improved after the drug was stopped,so it was eliminated.A patient in the Dumai Ironing group fell off because of going out and leaving Shengyang.A total of 75 people participated in the whole trial.2.ECG monitoring: After treatment,the ECG of the three groups was significantly improved.The total effective rate of the Baoyuan Decoction group was 44%(11/25),while that of the Dumai Ironing group was 64%(16/25),and the control group was 44%(11/25);the improvement of ECG in the Dumai Ironing Ironing group was higher than that in the control group(P<0.05);the difference between Baoyuan Decoction and the control group was not obvious(P> 0.05).3.Comparison of blood lipid levels: after treatment,conventional western medicine and Baoyuan Decoction group bonded group TC,LDL-C levels significantly decreased,and the degree of improvement than the level in the control group(P < 0.05),TG,HDL-C levels before treatment.compared no significant improvement(P>0.05),Dumai Ironing group and control group compared with before treatment,the difference was not statistically significant(P>0.05).4.TCM Body Mass Scale(Qi Deficiency): After treatment,the degree of Qi deficiency in the Baoyuan Decoction group and the Dumai Ironing group was greatly improved.Before the treatment,the score of Baoyuan Decoction group was 60.75±14.74,that of Dumai Ironing group score was 57.50±11.73,and that of the control group was 59.00±11.56;while the score of Dumai Ironing group,Baoyuan Decoction group and the control group was 46.88±19.26,48.63±16.59,and 57.50±16.21;and no significant difference in the scores between the Baoyuan Decoction group and the Dumai Ironing group has shown after treatment(P>0.05).5.Life quality SF-12 scale: After treatment,both physical and mental health scores of the Dumai Ironing group and the Baoyuan Decoction group have significantly soared,anxiety,depression and other emotions were significantly reduced;compared with the control group,the physical and mental health scores of the Baoyuan Decoction group were significantly increased(P<0.05);the mental health scores of the Dumai Ironing group were significantly increased(P<0.05).6.Seattle Angina Pectoris Scale: Varying degrees of improvements has shown to the onset and the stable state of angina pectoris in the three groups of patients.Significant increase has shown as for the scores of AS,TS,DS in the Baoyuan Decoction group comparing to the statistics before the treatment,and the point of AS was higher than that of the control group after treatment(P<0.05);all index in the Dumai Ironing group were significantly increased,of which AS,AF,TS,DS were higher than the points after treatment in the control group(P<0.05),while AF was higher comparing to the results of the Baoyuan Decoction group(P <0.05).7.No obvious adverse reactions shown in the three groups of patients.Vital signs of test objects were stable: the ALT,the AST,the blood and urine routines,creatinine and no significantly abnormal signs in safety indicators took place during the course of patient test,except for 1 object who had orbital pain and shedding.Conclusion:1.The method of Dumai Ironing or Baoyuan Decoction can reduce both the frequency and the symptoms of angina pectoris,while relieving depression and anxiety,improving the physique of Qi deficiency and patients’ survival quality when applied during the treatment of elderly patients with stable angina pectoris(qi deficiency syndrome)of coronary heart disease.2.Comparison of Baoyuan Decoction combined with conventional western medicine and conventional western medicine,TC,LDL-C levels of elderly patients with stable angina pectoris(qi deficiency syndrome)are improved after Baoyuan Decoction is applied.3.Comparing Dumai Ironing method combined with conventional western medicine and conventional western medicine,obvious improvement in the ECG level of elderly patients with stable angina pectoris(qi deficiency syndrome)appear after patients are applied with Dumai Ironing.4.Baoyuan Decoction and Dumai Ironing Method are both effective and safe while referring to the treatment of elderly patients with stable angina pectoris(qi deficiency syndrome). |
