| With the acceleration of modernization,the aging of the population is gradually increasing,and the number of senile diseases is also increasing,which makes the medical service industry face new difficulties and challenges,and greatly promotes the development of implantable medical equipment.Among many implantable medical devices,deep brain nerve stimulators have become a hot topic in many universities and research institutions because of their high integration and complexity.Traditional nerve stimulators rely on one-time battery power supply,when the battery energy is insufficient can only be replaced by surgery,causing additional physical pain and economic burden to patients.The general wireless energy transmission system can solve the problem of continuous power supply of the stimulator,but it still faces the problems of implant volume limitation,temperature and energy control during transmission.Based on the nerve stimulator project of the internship company,this paper designs a wireless power transmission system of nerve stimulator with smaller volume,controllable energy transmission and functions of overtemperature protection and wireless communication.The following aspects are mainly completed :(1)The working principle of the magnetic coupling resonant energy transfer technology is studied.Through the derivation and analysis of the transmission efficiency under four different topologies,the transmission circuit model suitable for this system is determined.Based on the characteristics of resonant coil,the magnetic coupling coil model is established in Maxwell simulation platform.The coil model is optimized by analyzing the influence of mutual inductance,transmission distance and turns on transmission efficiency.According to the simulation results,the feasibility of the proposed resonant coil model is verified in theory.(2)The hardware and software design of the system in vitro and in vivo are completed.CC1310 is used as the main control chip of the wireless energy transfer system of the nerve stimulator.The hardware part mainly includes control module,charging module,charging management module,wireless communication and modulation module and temperature measurement module.The charging module includes the inverter circuit and the sampling circuit.The module and the charging management module jointly realize the wireless transmission of system energy.The wireless communication module uses CC1310 internal RF core and modulation module to realize in vitro and in vivo information interaction.The software part mainly includes power self-regulation,sampling,serial port task and low power sleep,so that the system can automatically adjust the output power and monitor the temperature according to the collected coil information,so as to achieve the purpose of accurate and reliable energy supply for nerve stimulator.(3)The simulation and physical function test platform of the wireless power transmission system of nerve stimulator was built.The Simulink software in Matlab was used to establish the system circuit simulation model,which verified the rationality of the system circuit design.The function test of the system is completed.The charging efficiency,temperature rise and radio frequency communication are tested respectively.The accuracy test of the temperature detection module is completed before the temperature rise test.The data of serial port information transmission,coil output waveform,temperature rise curve and RF carrier frequency and bandwidth are obtained.Under the premise of meeting the basic power supply requirements of nerve stimulator,the effective transmission distance is increased to 25 mm,the temperature rise can be controlled within 2℃,and the carrier frequency offset is less than±20 ppm.Through comparative analysis,the system indicators are verified to meet the expected design.The innovation of this paper is to propose a coil model for the structure of implantable nerve stimulator,optimize the size of the coil and the number of turns,and find the best transmission distance.While satisfying the stable power supply of implantable nerve stimulator,compared with similar products on the market,the implant volume and weight are reduced,and the transmission distance is increased from 10 mm to 25 mm,which can effectively reduce the difficulty of surgery and the size of the wound.Frequency agility and sleep listening are added to optimize the antiinterference ability of RF wireless communication and reduce the communication power consumption.Finally,through simulation debugging and laboratory testing,the feasibility and rationality of the proposed scheme are verified at different levels,and it has great clinical application and market competition potential... |