Objective Arrhythmia is one of the most common complications of acute myocardial infarction,and fatal arrhythmia is also the main cause of death of acute myocardial infarction.Clinicians can identify risk factors,risk assessment for patients early,and then develope effective interventions for high-risk patients to improve the prognosis.Early assessment and effective interventions can improve patient outcomes.The aim of this paper is to analyze the relevance of myocardial injury and inflammatory markers to 30 days of mortality in patients of fatal arrhythmia after acute myocardial infarction.Methods From 2010 to 2015,1509 patients with acute myocardial infarction were collected from zhejiang provincial people’s hospital,including 120 cases of fatal cardiac arrhythmia.According to the exclusion criteria,the final group was 108 patients with fatal cardiac arrhythmia.Through clinical case data inquiry and telephone follow-up,the experimental data needed for the study were obtained.To analysis the relevance of myocardial lesion markers and inflammatory factors to 30 days of mortality in patients of fatal arrhythmia after acute myocardial infarction.Results(1)Compare the difference between patients’ age,gender,past medical history(hypertension,type 2 diabetes,hyperlipidemia,previous stroke,chronic myocardial infarction)and the patients’ 30 days all-cause mortality,there were statistically significant differences in age,type 2 diabetes,old myocardial infarction and hospitalization day(P<0.05).(2)To compare different levels of white blood cell(WBC)count,C-reactive protein values(CRP),B-type natriuretic peptide(BNP),troponin I,Low density lipoprotein cholesterol(LDL-C)and Left ventricular ejection fraction(LVEF)to the patients’ 30 days all-cause mortality of fatal arrhythmia after acute myocardial infarction,the level of WBC,CRP,troponin I,LDLC have no statistical difference(P>0.05),but different levels of BNP paribas,LVEF have statistical difference(P<0.05).(3)There was difference between the different infarction sites and the patients’ 30 days all-cause mortality,which was statistically significant(P<0.05).(4)Comparing whether patients underwent emergency PCI stenting with 30 days all-cause mortality,there was statistically significant(P<0.05).(5).(6)Logistic regression analysis revealed that the risk factors for fatal cardiac arrhythmias occurred during the hospitalization of patients with AMI:infarction areas and LVEF decreased.(5)The patients were grouped according to the rapid and slow arrhythmias,and the difference between the two groups was statistically significant(P<0.05).(6)Logistic regression analysis revealed that the risk factors for the patients’ 30 days all-cause mortality:the hospital day was less than 10 days,LVEF was less than 50%,and no emergency PCI stent was implanted.Conclusion(1)AMI was associated with a high all-cause mortality rate of 30 days in patients with fatal arrhythmia.(2)After AMI,fatal arrhythmia was more common in acute anterior wall myocardial infarction and acute lower wall myocardial infarction,and 30 days all-cause mortality was higher than other infarction sites.(3)In patients with fatal arrhythmia after AMI,rapid cardioarrhythmias were found to be significantly higher in 30 days all-cause mortality than in slow cardiotype.(4)The patients with AMI and fatal arrhythmias were able to rise in WBC and CRP,but these had no correlation with the patients’ 30 days all-cause mortality.(5)CTnI and BNP were elevated in patients with fatal arrhythmia after AMI,but these had no correlation with the patients’ 30 days all-cause mortality.(6)The levels of LDL-C in AMI patients with fatal arrhythmias were not correlated with 30 days all-cause mortality.(7)Patients with fatal arrhythmias after AMI,LVEF less than 50%,were predictors of 30 days all-cause mortality.(8)An acute PCI stent implantation in patients with fatal arrhythmia after AMI can significantly reduce the 30 days all-cause mortality. |