Ultrasound In Pregnancy Complicated With Subclinical Hypothyroidism In Pregnant Women Of Fetal Thyroid Gland Morphology Study On The Relationship Between

Objective 1.Use of ultrasound in fetal thyroid gland morphology,rule of change with weeks of thyroid,explore the fetal thyroid related reference values.2.Observation of subclinical hypothyroidism in pregnant women of fetal morphological changes of thyroid gland,ultrasonography in prenatal assessment combined subclinical hypothyroidism in pregnant women of fetal thyroid function of practical value and merit.3.Obtained through ultrasound fetal thyroid volume ratio of total body weight,get the fetal thyroid gland score.MethodsFrom October 2016 May 2017 at our hospital to undergo routine Prenatal ultrasound examinations of pregnant 24-40 weeks of 240 cases were divided into two groups of pregnant women,aged 22～40sui,which diagnosed subclinical hypothyroidism in 40 cases of pregnant women as a group,for randomly selected 200 healthy pregnant women in the control group,Singleton,Exclude thyroid disease and other systemic diseases.Ultrasound examination for fetus and its appendages,focus observe fetal thyroid gland morphology,were measured by ultrasound of fetal biparietal diameter,head circumference,abdominal circumference,femur length,index,heart rate,S/D of umbilical artery and amniotic fluid and fetal thyroid width,diameter,diameter,calculation of fetal thyroid volume and frequency of fetal breathing and movement,Calculation of fetal biophysical profile score(BPS),according to the formula to calculate the fraction of thyroid gland(thyroid fraction=volume/fetal weight,fetal thyroid gland).Observation on pregnancy outcomes indicators:premature baby,small for gestational age infants,neonatal hypothyroidism,cesarean rates,such as anaemia in pregnant women and neonates with asphyxia.Statistical analysis on the above index.Observation of fetal thyroid 95%confidence interval data over the control group,fetal heart rate is greater than 160 beats/min or less than 120 times/min,was viewed with suspicion-positive cases,observation of fetal thyroid after birth blood measurement of TSH and T4.Results 1.Transverse diameter of the fetal thyroid gland in the control group,before and after the diameter,the diameter increases with the measured values increased with gestational age,is a clear linear relationship with gestational age,build the regression equation as follows:horizontal size and gestational age regression equation Y=0.042X-0.402,R2=0.854,P<0.05;Diameter and gestational age regression equation:Y=0.025X-0.180,R2=0.8,P<0.05;Upper and lower size and gestational age regression equation:Y=0.055X-0.367,R2=0.849,P<0.05.2.Observation group in premature infants,gestational age,fetal distress and neonatal screening to identify neonatal thyroid hypofunction,cesarean rates,maternal anaemia and the incidence of neonatal asphyxia was significantly higher than the control group,a statistically significant difference(P<0.05).3.Fetal thyroid testing data in the observation group than in the control group 95%confidence interval of 3 cases,fetal heart rate fastest in 2 cases(>160/min),2 cases of heart rate slow(<120 times/min),born after the 2 cases of elevated TSH,T4 lowering 1,critical high value 1.4.The study group and control group within their respective groups of fetal BPS grade compare and S/D values,respectively,the results show follows:late pregnancy fetal scores of BPS in the observation group were significantly lower than during pregnancy,both statistically significant(P<0.05),and draw the two groups had no significant differences(P>0.05);②Control group in late pregnancy fetal S/D and BPS scores were significantly lower than in the pregnancy,the difference was statistically significant(P<0.05).③And observation group and the control group between two groups of different weeks of gestation the fetus S/D values and compare BPS respectively,results showed that pregnancy in S/D and BPS scores in both groups showed no significant difference(P>0.05),late pregnancy fetal scores of BPS in the observation group were significantly lower than control group during pregnancy the fetus,Statistically significant differences(P<0.05),and late pregnancy S/D values between the two groups is unfortunately no significant difference(P>0.05).5.Color Doppler ultrasound echoes fetal thyroid gland,thyroid function in normal fetuses can be seen inside a stub-like color Doppler flow signals;Most of the fetuses of pregnant women with subclinical hypothyroidism normal control group.Observed three cases of thyroid in measurement data than that in the control group increased,95%confidence interval than the control group.6.Control of fetal thyroid volume,weight,thyroid score value increases with gestation,is a clear linear relationship with gestational age,build the regression equation as follows:size and gestational age regression equation:Y=0.094X-2.15,R2=0.861,P<0.05;Weight and gestational age regression equation:Y=0.182X-3.674,R2=0.958,P<0.05;Thyroid scores and gestational age regression equation:Y=0.012-0.003,R2=0.356,P<0.05Conclusion1.the use of color Doppler ultrasonography on fetal thyroid gland examination and measurement,access to a normal thyroid size range of different gestational age of the fetus,which was positively correlated with weeks of gestation,provide reference for hypothyroidism fetal diagnosis,abnormal fetal thyroid function of early detection and treatment.2.ultrasonic observation of pregnant women with subclinical hypothyroidism in pregnant women of fetal thyroid gland morphology,normal fetal thyroid function,thyroid is visible in the short-term-color flow signal;Most of the fetuses of pregnant women with subclinical hypothyroidism normal control group;Fetal thyroid gland and hypothyroidism increases,reduced blood flow distribution,characterized by surrounded.3.establish reference values of normal fetal thyroid fraction,access to data is a clear linear relationship with gestational age,can be further increased for the diagnosis of fetal thyroid dysfunction.