Contrast Application Of Intraoperative Fluorescence And Intraoperative Ultrasound In Glioma Surgery

Objective Comparative analysis was performed to determine the role of residual tumor in the operation of glioma.Methods A total of 24 patients with intracranial glioma treated by neurosurgeon in quzhou hospital from October 2016 to January 2018 were selected.successively applied after completion of glioma surgery to remove residual tumor,ultrasound and fluorescence judgment according to the judgment of residual tumor from ultrasound images and fluorescence imaging,ultrasonic tip respectively in(a)there are residual,(b)us no residue(c)fluorescence indicates a residue(d)fluorescence suggest no residue in pathological biopsy samples were randomly selected.statistical pathological findings.Results A total of 24 patients were enrolled in a total of 145 specimens,of which the fluorescence group(c,d)75,the ultrasound group(a,b)70,the pathology confirmed the residual tumor was 69,non-residual tumor 76.1.The sensitivity of the yellow fluorescence group(32/37 = 86.5)was greater than that of the ultrasonic group(22/32 = 68.8%),and the difference was not statistically significant(P > 0.05).The specificity of ultrasonic group(35/38 =92.1%)was greater than that of yellow fluorescence group(34/38 =84.2),and the difference was not statistically significant(P > 0.05).2.The sensitivity of ultrasonic group(9/12 = 75.0%)was higher than that of the yellow fluorescence group(9/13 = 69.2%),and the difference was not statistically significant(P > 0.05).The specificity of ultrasonic group(21/22 =95.5%)was higher than that of yellow fluorescence group(10/15 =66.7%),and the difference was statistically significant(P < 0.05).3.The sensitivity of yellow fluorescence group(23/24 = 95.8)was greater than that of ultrasonic group(13/20 = 65.0%),and the difference was statistically significant(P < 0.05).The specificity of yellow fluorescence group(22/23 =95.7%)was greater than that of the ultrasonic group(14/16 =87.5%),and the difference was not statistically significant(P > 0.05).4.Inside yellow fluorescent group,of low and high grade glioma residual boundary judgment have bigger difference,the sensitivity compared with specific degrees,high grade glioma residual judgment were greater than low grade gliomas,the difference was statistically significant(P < 0.05).5.In the ultrasound group,of low and high grade glioma residual boundary judgment have bigger difference,the sensitivity compared with specific degree,low grade gliomas residual judgment were greater than the high level of glioma,there was no statistically significant difference(P > 0.05).Conclusion 1.In determining the residual boundary of glioma,both yellow fluorescence and intraoperative ultrasound have high sensitivity and specificity.2.Intraoperative ultrasound can better display the boundary of low-grade glioma,and fluorescence can better display the boundary of high-grade glioma.3.In the judgment of the residual boundary of the low-grade glioma,the yellow fluorescence development was not obvious,and the sensitivity and specificity declined.In the judgment of the residual boundary of high grade glioma,the judgment of ultrasound on the boundary was difficult to be recognized,although both sensitivity and specificity were decreased,but no statistically significant difference was found.4.The sample size of this study is small,and there is no matching study,and the reliability needs further study and verification.