| Objective: To observe the clinical effect of modified Zhengan Xifeng decoction in treating yin deficiency and hyperactivity of fire,so as to expand the thinking and methods of treating insomnia of Parkinson’s disease with traditional Chinese medicine.Methods: Sixty-six patients who met the diagnostic criteria were randomly divided into treatment group and control group,33 patients each.The treatment group was treated with Madopar and modified Zhengan Xifeng decoction.The control group was treated with eszopiclone combined with Madopar.Both groups were treated for four weeks.The clinical efficacy was determined at the end of the treatment course,and the scores of Webster Scale,Pittsburgh Sleep Quality Index Scale,and TCM Hyperactivity of Fire due to Yin Deficiency Score Scale were observed before and after treatment.The obtained data were statistically analyzed by SPSS 26.0.Results: Two cases in the control group and 3 cases in the treatment group were lost.There were 31 cases in the final control group and 30 cases in the treatment group.The total effective rate of the treatment group was93.33%,while that of the control group was 83.87%.After inspection,the total clinical efficacy of the treatment group was better than that of the control group.The treatment of the control group had clear efficacy in terms of sleep improvement,improvement in motor symptoms of Parkinson’s disease,and minor efficacy in terms of TCM symptoms,while the treatment of the treatment group had significant efficacy in all three aspects of symptoms.There were no obvious adverse events during the treatment,and the curative effect and safety were clear.Conclusion: Modified Zhengan Xifeng decoction has good clinical effect on insomnia in Parkinson’s disease with yin deficiency and fire hyperactivity,which can significantly improve the subjective sleep quality of patients and relieve impatience without obvious side effects,and the curative effect is exact and safe. |
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