| Objective:To study the distribution law of TCM constitution of patients with bronchiectasis in stable stage.To investigate the BSI score of patients in stable stage of bronchiectasis.To explore the correlation between TCM constitution types and BSI scores in patients with stable bronchiectasis,so as to provide new ideas for the assessment of disease risk of patients with bronchiectasis from the perspective of TCM.Methods:In this study,119 patients with bronchiectasis in stable stage were collected from January2021 to February 2022 in the Department of Respiratory Medicine,Affiliated People’s Hospital of Fujian University of Traditional Chinese Medicine.The researchers collected relevant basic information,specialized materials,TCM constitution types,BSI scores and stratified results,etc.,and analyzed the characteristics of TCM constitution,and whether there was a connection between TCM constitution and related clinical indicator.Results:（1）Among the 119 subjects,there were 52 male patients（43.7%）and 67 female patients（56.3%）,and the ratio of male to female was 1:1.29.The average age of the subjects was61.27 10.40 years old,with the oldest being 86 years old and the youngest being 29 years old.In descending order,the number of people in different age groups is as follows:60 to 69 years old is the most,with 42 cases（35.3%）,50 to 59 years old with 38 cases（31.9%）,70 years old and above with 27 cases（22.7%）and under 50 years old with 12 cases（10.1%）.The duration of bronchiectasis was less than 1 year in 9 cases（7.6%）,1 to 5 years in 23 cases（19.3%）,6 to10 years in 30 cases（25.2%）,and 10 years or more accounted for the highest proportion,with57 cases（47.9%）.（2）The main TCM constitutions of 119 subjects were distributed as follows:29 cases（24.4%）were of Qi-deficiency type,21 cases（17.6%）were of Yang-deficiency type,15 cases（12.6%）were of Yin-deficiency type,12 cases（10.1%）were of Phlegm-wetness type,11 cases（9.2%）were of Qi-depression type,10 cases（8.4%）were of Wet-heat type,8 cases（6.7%）were of Gentleness type,7 cases（5.9%）were of Blood-stasis type,each of which had the fewest Special diathesis type,with only 6 cases（5.0%）.（3）The distribution of constitution types in TCM is different on the age（P<0.05）.Yang deficiency type was related to the advanced age.（4）There was no significant difference in gender distribution of different TCM constitution types（P>0.05）,and the proportions of male and female patients with different constitution types were about the same.（5）The distribution of BMI index among different TCM constitution types was different（P<0.05）.The patients with Yin-deficiency type and Yang-deficiency type collateral enlargement were related to low BMI,while the Phlegm-wetness type was related to high BMI.（6）The distributions of FEV1%pred and m MRC scores of different TCM constitution types were different（P<0.05）.The lung function level of patients with bronchiectasis of Qi-deficiency type and Yang-deficiency type was significantly lower,while the m MRC score was significantly higher.（7）The distribution of annual acute exacerbation times among different TCM constitution types was different（P<0.05）.Among them,the patients with bronchiectasis of Phlegm-wetness type,Yang-deficiency type and Qi-deficiency type were related to the more frequent annual acute exacerbation times.（8）The distribution of the number of lung lobes involved was different among the TCM constitution types（P<0.05）.For the patients with Yang-deficiency type,the number of lung lobes involved was significantly more.（9）The constitutions of different TCM physicians distributed differently in the risk stratification of BSI（P<0.05）.For intra-group comparison,the specific distribution according to frequency statistics was as follows:mild group:Gentleness type and Qi-depression type;moderate group:Qi-deficiency type and Yang-deficiency type;severe group:Yang-deficiency type,Qi-deficiency type,Yin-deficiency type and Phlegm-wetness type.Among them,Phlegm-wetness type was significantly correlated with high BSI score and severe BSI hierarchical level.Conclusion:（1）In the stable stage of bronchiectasis,biased constitution was dominant,and Qi deficiency,Yang-deficiency,Yin-deficiency and Phlegm-wetness types were the most common constitution types in TCM.（2）TCM constitution of patients with bronchiectasis is related to indexes of disease severity.The patients with bronchiectasis of Yin-deficiency type and Yang-deficiency type had low body weight.The Phlegm-wetness type was related to the high body mass index.Patients with bronchiectasis due to Qi-deficiency type and Yang-deficiency type had worse pulmonary function.For the patients with bronchiectasis with Phlegm-wetness type,Yang-deficiency type and Qi-deficiency type,the annual acute exacerbation was more frequent.Patients with bronchiectasis due to Qi-deficiency type and Yang-deficiency type are more likely to have dyspnea.In patients with bronchiectasis due to Yang-deficiency type,the scope of pulmonary lobectomy damage is more extensive.（3）In the mild group with BSI risk stratification,Gentleness type and Qi-depression type were dominant,while Qi-deficiency type and Yang-deficiency type were dominant in the moderate group.In the severe group,Yang-deficiency type,Qi-deficiency type,Yin-deficiency type and Phlegm-wetness type were dominant.Among them,the disease severity（BSI）is higher in the patients with Phlegm-wetness type branch enlargement,and it is more likely than other constitution types to have acute aggravation and poor prognosis outcome in the future. |
