Analysis On The Distribution Of TCM Syndrome TyPes And Related Factors After LaParoscoPic Radical Resection Of Colorectal Cancer

Objective: to understand the distribution of TCM Syndrome Types on the 7th day after operation of colorectal cancer,and further explore whether there is correlation between different syndrome types and intraoperative factors(intraoperative bleeding,intraoperative rehydration,operation time,surgical resection scope and intraoperative lymph node dissection),and finally try to find the intraoperative independent influencing factors affecting the distribution of syndrome types on the 7th day after operation of colorectal cancer,including intraoperative risk factors and intraoperative protective factors.The purpose is to provide some ideas and suggestions for TCM syndrome differentiation and TCM Intervention on the 7th day after colorectal cancer surgery(i.e.the patient will be discharged or after discharge).Methods: This study is a cross-sectional study.The trained graduate students recorded the amount of intrao Perative bleeding,intraoperative fluid replacement,operation time and resection range from the operation record sheet of each enrolled case;The number of lymph node dissections and pathological data were recorded from the postoperative pathological report.On the 7th day after operation,two or more TCM doctors were responsible for syndrome differentiation,and the syndrome types of the patients were recorded.The observed data shall be recorded in the clinical case observation table and excel table at the same time.The data were statistically analyzed by SPSS 22.0.Result:1.The maximum age of patients with colorectal cancer is 84 years old and the minimum age is 30 years old,and there are differences in the distribution of people in different age groups(p < 0.05).There are 75 people in the elderly group(60 years old and above),21 people in the middle-aged group(45 years old and above,under 60 years old)and 7 people in the young group(under 45 years old).There were 56 male patients and 47 female patients.The ratio of male to female was 1.19:1,and there was no difference between the two(p >0.05).There were significant differences in the distribution of TNM stages in patients with colorectal cancer.The distribution of each stage was as follows: stage III(56.73%)> stage II(25%)> stage I(13.46%)> stage IV(4.81%).There are differences in the distribution of tissue type,gross type and degree of differentiation in the postoperative pathology of colorectal cancer,and the most common type is moderately differentiated ulcerative adenocarcinoma.2.There are significant differences in the distribution of TCM Syndrome types on the 7th day after operation of colorectal cancer.The order of distribution is: spleen deficiency and qi stagnation syndrome(40 cases)> liver and kidney yin deficiency syndrome(30 cases)> Qi and blood deficiency syndrome(22 cases)> spleen and kidney yang deficiency syndrome(11cases).3.Single factor analysis: Chi square test showed that there was a significant correlation between intraoperative bleeding,intraoperative fluid replacement and operation time and postoperative TCM syndrome types(p < 0.05).There was no significant correlation between the number of lymph node dissection and the scope of surgical resection and the type of TCM syndrome after operation(p> 0.05).4.Multivariate analysis: by binary logistic regression analysis,the operation time ≥ 210 minutes was the independent risk factor of spleen deficiency and qi stagnation syndrome on the 7th day after operation of colorectal cancer(p = 0.017,OR = 3.491);operation time < 210 minutes was an independent protective factor of liver and kidney yin deficiency syndrome on the 7th day after operation of colorectal cancer(p = 0.018,OR = 0.247).Conclusion: This paper finds out that there is a correlation between three intraoperative factors of colorectal cancer and postoperative TCM syndrome types.Operation time is not only an independent risk factor of postoperative spleen deficiency and qi stagnation syndrome,but also an independent protective factor of postoperative liver and kidney yin deficiency syndrome.It not only provides some help for exploring the influencing factors of postoperative TCM syndrome types of colorectal cancer,but also provides more ideas for postoperative TCM dialectical intervention of colorectal cancer.