| Objective: By observing the clinical efficacy of Lixue Heluo Decoction in treating patients with postoperative angina pectoris(qi stagnation and blood stasis)after PCI.Methods: From December 2021 to December 2022,90 patients with stable angina after PCI of qi stagnation and blood stasis in the Department of Cardiology of the Affiliated Hospital of Shandong University of Chinese Medicine were selected and randomly divided into the experimental group and the control group,45 cases in each group.On the basis of the control group,the experimental group was added with Lixue Heluo Decoction.After 8 weeks of treatment,angina pectoris symptoms,CCS angina pectoris classification,TCM syndrome score,6-minute walking test,reduction rate of triglyceride,low-density lipoprotein and nitroglycerin in the two groups were observed before and after treatment.Statistical correlation analysis was used to evaluate the clinical effect of Lixue Heluo Decoction on stable angina pectoris after PCI(qi stagnation and blood stasis syndrome).Results:1.A total of 90 patients with qi-stagnation and blood-stasis type of stable angina after PCI were enrolled in this study.During diagnosis,treatment and follow-up,6 cases were dropped out and eliminated in the control group,and 39 cases remained,while 5 cases were dropped out and eliminated in the experimental group,and 40 cases remained.2.Angina pectoris score and total TCM syndrome score: Before treatment,angina scores of experimental group(5.82±1.723)and control group(5.79± 1.704).After 8 weeks of treatment,the effective rate of angina in experimental group was 87.50%,and that in control group was 61.54%.These data were statistically significant differences(P < 0.05).The treatment effect of experimental group was higher than that of control group.Before treatment,the total score of TCM syndrome in the experimental group was 16.02±2.201,and that in the control group was 15.97±2.206.After 8 weeks of clinical treatment,the total effective rate in the experimental group was87.50%,and that in the control group was 51.28%,with statistical difference in rank sum test(P < 0.05).The effectiveness of experimental group was stronger than that of control group.3.Nitroglycerin reduction rate: After 8 weeks of treatment,the reduction rate of nitroglycerin in the experimental group was 82.50%,and the reduction rate of nitroglycerin in the control group was 56.41%.The rank sum test showed a significant difference(P < 0.05),and the reduction rate in the experimental group was better than that in the control group.4.CCS angina pectoris classification: After 8 weeks of treatment,the CCS of the experimental group was grade I(15%)and grade II(57.5%),accounting for 72.5%.In the control group,grade I patients accounted for 5.1%,grade II patients accounted for 48.7%,and the total proportion was 53.8%.The rank sum test showed statistical difference between the two groups(P < 0.05),and the CCS of the experimental group was better than that of the control group.5.6 minute walk test: before treatment,6 minute walk test in the experimental group was(420.08±53.504),and 6 minute walk test in the control group was(418.92±52.199),and there was no significant difference between the two groups(P > 0.05).After 8 weeks of treatment,experimental group(509.40±52.62),control group(464.41±52.00);T-test showed statistical difference(P < 0.05),and the experimental group had better therapeutic effect in the 6-minute walking test.6.Triglycerides,LDL:Before treatment,the triglyceride levels in the experimental group(2.66±0.467)and the control group(2.65±0.456)were significantly lower than those in the control group(P < 0.05).After 8 weeks of treatment,the triglyceride levels in the experimental group(2.13±0.476)and the control group(2.35±0.465)were lower than those in the control group(P < 0.05).Before treatment,the low-density lipoprotein in the experimental group was(3.16±0.469),and the low-density lipoprotein in the control group was(3.15±0.45).After 8 weeks of treatment,the low-density lipoprotein in the experimental group was(2.45±0.472),and the low-density lipoprotein in the control group was(2.84±0.46).The low-density lipoprotein level in the experimental group was lower than that in the control group(P < 0.05).Conclusions: The results show that Lixue Heluo Decoction has obvious curative effect on stable angina pectoris after PCI of qi stagnation and blood stasis syndrome,which can relieve the pain of angina patients and improve the quality of life,and has more advantages than Western medicine treatment alone.Lixue Heluo Decoction can be used for the clinical treatment of stable angina pectoris after PCI(qi stagnation and blood stasis syndrome). |
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