| Objectives To investigate the short-term efficacy and safety of transuerthral enucleation and resection of the prostate(TUREP)and Transurethral resection of prostate(TURP)in patients with benign prostatic hyperplasia(BPH)and in the middle of treatment.Methods Clinical data of 95 BPH patients treated and followed up in the Department of Urology of Tangshan Workers’ Hospital from November 2020 to November 2021 were collected.The patients were randomly divided into observation group(47 cases)and control group(48 cases).Two groups of patients with preoperative information collection(age,prostate volume),intraoperative data(operation time,resection of the prostate and the decrease of the hemoglobin value)and postoperative data(bladder irrigation duration,urine tube indwelling time,postoperative hospitalization time,intraoperative and postoperative physiological saline usage)and preoperative and postoperative 3 months data(residual urine volume,PSA,IPSS,QOL),complications,etc.To compare the short-term efficacy and safety of TUERP and TURP in medium and large volume BPH surgery.Results 1 All patients successfully completed surgery.There was no significant difference in preoperative general data between 2 groups(P>0.05).2 The prostate resection rate in TUERP group was significantly higher than that in TURP group [(53±8.9)%vs.(42±6.0)%](P<0.05);Perioperative indicators of TUERP group were better than TURP group(P<0.05): Decreased hemoglobin(11.00±6.53 vs.16.56±6.79)g/L,operative time(64.85±15.40 vs.90.21±13.41)min,bladder flushing time(11.96±1.71 vs.14.46±1.60)h,catheter indwelling time(42.30±1.4)1vs.60.46±6.37)h,postoperative hospital stay(2.83±0.70 vs.3.85±0.71)d,intraoperative and postoperative flushing fluid usage(61.36±22.66 vs.79.35±31.07)L.3 There was no significant difference in postoperative urine flow rate visual scale score between the two groups(P>0.05).There were no significant differences in IPSS score,QOL score and residual urine volume between the TUERP group and the TURP group three months after surgery(P>0.05):(5.96±2.03 vs.6.65±2.02),(1.34±0.82 vs.1.38±0.79),[4(0～10)vs.5(0～11.5)]mL.The PSA reduction rate3 months after operation in TUERP group was significantly higher than that in TURP group [(67±15.3)% vs.(47±15.4)%],the difference was statistically significant(P<0.05).4 There were 4 complications in TUERP group,including 2 cases of urge incontinence(4.3%),1 case of postoperative fever(2.1%),and 1 case of urinary retention(2.1%).There were 5 TURP complications,including 1 case of urge incontinence(2.1%),2 cases of postoperative fever(4.2%),and 2 cases of secondary bleeding(4.2%).5 TUERP in different volume stratification,prostate resection rate and PSA reduction rate were better than TURP group,the differences were statistically significant(P<0.05).Conclusions 1 In TUERP and TURP,both medium and large volume BPH can give patients a definite curative effect.However,TUERP has more advantages in the minimally invasive treatment of medium and large volume BPH.2 TUERP improved the glandular excision rate of medium and large volume BPH,and the postoperative PSA reduction rate was more significant,so it was inferred that the possibility of long-term postoperative reoperation rate was lower.Figure 5;Table 11;Reference 102... |
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