| Objectives Through the systematic review of literature on the clinical research of peripheral facial paralysis and a questionnaire survey of acupuncturists,this research preliminarily discusses the influence of different time factors on the effect of acupuncture and moxibustion for this disease,hoping to provide directions for future clinical research.Methods Systematic review: the research collected the literature of clinical randomized controlled study on acupuncture and moxibustion for peripheral facial paralysis through the retrieval of CNKI,Wanfang Data,VIP database,and Pub Med database with the retrieval time from January 1st,2000 to December 31 th,2021.The extracted data was entered into Excel to establish a database,and the statistical software of Review Manager5.3 was applied to conduct statistical analysis.Physician survey: from January 2021 to January 2022,the research adopted the questionnaire of “Questionnaire of Time Factor and Acupuncture Effect-Physician Version” to survey 85 clinicians engaged in the treatment of acupuncture and moxibustion.The survey data was input into Excel to establish a database,and the statistical software of SPSS 23.0 was applied to conduct statistical analysis.Results 1 Meta-analysis of time factor effect of acupuncture and moxibustion on peripheral facial paralysis: 28 clinical randomized controlled trials were included,by which the research found: 1)Intervention time:(1)The total effective rate of intervention of acupuncture and moxibustion for peripheral facial paralysis within 7 days was higher than that after 7 days(OR=1.12,95%CI: 1.07-1.17,P<0.01);(2)The recovery rate of intervention within 7 days was higher than that after 7 days(OR=1.36,95%CI: 1.23-1.51,P<0.01);(3)The average recovery time of intervention within 7 days was shorter than that after 7 days(OR=13.34,95%CI: 11.39-15.29,P<0.01);(4)In the improvement of Portmann score,the intervention within 7 days was better than that after 7 days(OR=6.37,95%CI: 5.90-6.84,P<0.01);2)Duration of needle retention:(1)The recovery rate of acupuncture and moxibustion for peripheral facial paralysis with about 20 minutes of duration of needle retention was higher than that with about 30 minutes(OR=2.14,95%CI:1.54-2.97,P<0.01);(2)The average recovery time of acupuncture and moxibustion for peripheral facial paralysis with 19 minutes of duration of needle retention was shorter than that with about 30 minutes(WMD=4.02,95%CI: 1.39-6.65,P<0.01);3)Interval of time:(1)There was no significant difference in the effect of acupuncture and moxibustion for peripheral facial paralysis at intervals of 2～3 times/week and 5～6 times/week(OR=0.99,95%CI: 0.94-1.05,P>0.05);(2)In the improvement of HB score,the treatment of acupuncture and moxibustion for peripheral facial paralysis at an interval of 3 times/week was better than that at an interval of 6 times/week(OR=1.34,95%CI: 0.16-2.51,P<0.05);(3)In the improvement of FDI physiology score,acupuncture treatment for peripheral facial paralysis at an interval of 3 times/week was better than that at an interval of 6times/week(OR=0.62,95%CI: 0.06-1.17,P<0.05);(4)In the improvement of FDI society score,acupuncture treatment for peripheral facial paralysis at an interval of 3 times/week was better than that at an interval of 6 times/week(OR=0.63,95%CI: 0.23-1.03,P<0.01).2Experience survey on the time-effect relationship of acupuncturist in treating peripheral facial paralysis: 85 acupuncturist were included,by which the research found: 1)Intervention time: 94.12% of acupuncturist thought that the optimal intervention time for acupuncture treatment of peripheral facial paralysis was the acute phase;2)Needle retaining time: 47.1% of acupuncturist thought that the optimal needle retaining time was20 minutes in the acute phase,75.3% of acupuncturist thought that the optimal needle retaining time was 30 minutes in the recovery phase,63.5% of acupuncturist thought that the optimal needle retaining time was 30 minutes in the sequelae phase,there were significant differences in the needle retaining time which chosen by acupuncturist in the three phases(P<0.01).3)Interval time: 42.4% of acupuncturist thought that the optimal interval time was 3 times/week in the acute phase,48.2% of acupuncturist thought that the optimal interval time was 3 times/week in the recovery phase,45.9% of acupuncturist thought that the optimal interval time was 3 times/week in the sequelae phase,there were no statistically differences in the interval time which chosen by acupuncturist in the three phases(P>0.05).4)Course of treatment: 52.94% of acupuncturist thought that the course of treatment was 16 to 21 days in the acute phase,77.64% of acupuncturist thought that the course of treatment was 3 to 6 weeks in the recovery phase,55.29% of acupuncturist thought that the course of treatment was 5 to 6 weeks in the sequelae phase.Conclusions 1 The optimal intervention time for peripheral facial paralysis is the acute phase(within 7 days).2 The optimal duration of needle retention is 20 minutes in the acute phase and 30 minutes in the recovery and sequelae phases.3 The optimal interval of time is 3 times/week.4 The course of treatment in the acute phase is usually 16 to 21 days,and the recovery and sequelae phases can be appropriately extended.There is no exact standard for the optimal course of treatment,and clinical randomized controlled trials can be carried out for further research and discussion.Figure 18;Table 19;Reference 94... |
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