Comparison Of Clinical Characteristics And Risk Factors Of Ischemic Colitis In Different Age Groups

Objective By comparing the clinical characteristics and risk factors of ischemic colitis in different age groups,the clinical characteristics of ischemic colitis in different age groups can be further analyzed,so that the high-risk groups of ischemic colitis in different age groups can be identified at an early stage and timely and reasonable interventions can be made to reduce the rate of underdiagnosis and misdiagnosis in the clinic.Method(1)A total of 120 eligible IC subjects who were hospitalized in the Department of Gastroenterology of the First People’s Hospital of Hefei from January2015 to May 2022 were selected as the case group,and 40 subjects were from the young and middle-aged group(age<60 years),80 were from the elderly group(age ≥60 years).A control group of 120 hospitalized patients with colorectal polyps who underwent colonoscopy during the same period,excluding those diagnosed with IC,and 40 patients from the young and middle-aged group(age < 60 years),80 were from the elderly group(age ≥60 years).First,the clinical data of IC in the case group and the control group were compared,and the differences in clinical characteristics of IC in different age groups were analyzed.(2)The past medical history,surgical history,medication history and other data of the case group and the control group were compared to analyze the risk factors of IC in different age groups.Results(1)By comparing the data between the young and middle-aged group and the elderly group in the case group,the results showed that the initial clinical manifestations of the two groups were mainly abdominal pain and hematochezia,and the difference was not significant.There were no significant differences in coronary heart disease,atrial fibrillation,sinus bradycardia,hyperlipidemia,cholecystolithiasis,chronic gastritis,history of abdominal surgery,fatty liver,constipation,hyperuricemia and the use of rifampicin,lipid-lowering drugs,ACEI,CCB drugs between the elderly group and the young and middle-aged group.The incidences of cerebral infarction,hypertension,diabetes and NSAIDs in the young and middle-aged group were significantly lower than those in the elderly group.The albumin level of the elderly group was significantly lower than that of the young and middle-aged group.The main findings of abdominal CT examination in the two groups were intestinal wall thickening and edema,and the difference was not significant.Under colonoscopy,the left colon was more common in the two groups,and the main manifestations were congestion,erosion and edema under the microscope,and the difference was not significant.Both groups were given medical conservative treatment,and were improved and discharged.(2)Comparison of past medical history,surgical history,medication history and other data between the case group and the control group showed that the proportion of women,history of abdominal surgery,hypertension and diabetes in the elderly case group were significantly higher than those in the elderly control group.The proportion of females and history of abdominal surgery in the young-middle-aged case group were significantly higher than those in the young-middle-aged control group.Multivariate regression analysis showed that female was the risk factor for IC in the young and middle-aged,while female,hypertension and diabetes were the risk factors for IC in the elderly.Conclusion(1)Compared with young and middle-aged IC patients,the elderly IC patients are more likely to have hypertension,cerebral infarction,diabetes,NSAIDs and other basic medical history;The results of laboratory tests showed that the albumin level in the elderly group was significantly lower than that in the young and middle-aged group.Female is the risk factor for IC in the young and middle-aged,while female,hypertension and diabetes are the risk factors for IC in the elderly.