| Objective:To analyze whether there are differences between core bacteriology and surface bacteriology of tonsils in patients with chronic tonsillitis,as well as drug sensitivity,so as to guide clinical treatment.Methods: 110 patients diagnosed with chronic tonsillitis and underwent surgery in our hospital from January 2021 to January 2023 were selected,and 220 specimens were obtained from tonsil surface swabs and core bacterial culture during the surgery.Compare the bacterial culture results between two groups of samples using chi square test for any differences.Results: In addition to the normal bacterial community,17 bacteria were also isolated,with Staphylococcus aureus being the most commonly detected bacteria among Gram positive bacteria,found in 41.75% of the samples,followed by β-Hemolytic Streptococcus,other bacteria found in the core include Gram negative bacteria such as Haemophilus influenzae,Pseudomonas aeruginosa,and Klebsiella pneumoniae,among which there are differences in the distribution of Haemophilus influenzae surface and core bacteria.The difference in the detection rates of Gram positive bacteria and Gram negative bacteria among adult patients is relatively small,but the detection rate of Gram negative bacteria is higher compared to the children’s and adolescent groups.Conclusion::There is a difference between surface bacteria and core bacteria.A rich bacterial community can be found in the core,which is different from surface bacteria.The discovery of both surface and core bacterial communities suggests that Gram positive bacteria are more common,indicating that core samples are more likely to detect pathogenic bacteria,and the conclusion of drug sensitivity experiments is more therapeutic.The drug sensitivity test showed that Gram positive bacteria had a high resistance rate to penicillin,clindamycin,compound sulfamethoxazole and erythromycin,while Gram negative bacteria had a high resistance rate to piperacillin and ampicillin. |