| Objective: This study mainly analyzed the general data,clinical symptoms,laboratory indicators,imaging examinations,treatment and prognosis of children with mycoplasma pneumoniae lobar pneumonia retrospectively.The aim is to improve the understanding of such diseases and thus provide some reference for clinical work.Research methods: A total of 157 children diagnosed with LP due to MP infection and hospitalized in our department from January 2019～June 2022 in the Heping Campus of the Northern Theater General Hospital were included as the study population,divided by age < 5-year-old group and ≥-5-year-old group;According to the condition,it is divided into: with complications group and without complications group.All 157 children underwent chest imaging,and within 24 hours of admission,throat swab culture and venous blood were drawn for a number of laboratory index tests,and general information(gender,age,season of onset,length of hospital stay),clinical manifestations,pulmonary signs,complications,treatment and prognosis were collected.SPSS 23.0 was used to statistically analyze the data.Result:1.A total of 157 eligible children with Mycoplasma pneumoniae lobar pneumonia were collected,including 64 males and 93 females;the average age of illness was 6.0±2.3years old.Among them,118 cases(75.2%)were aged ≥ 5 years old,and there was no statistically significant difference between different ages and sexes;winter and autumn are the most common seasons in northern China.2.Cough(accounting for 100%)and fever(accounting for 95.5%)were the most common symptoms,with an average temperature of 39.4±0.6°C and an average duration of fever of 7.1±2.7;the <5-year-old group was more prone to wheezing(P<0.05);pulmonary rales tend to appear in the middle and late stages,and children with complications accounted for nearly 1/3 of this study.Hypoxemia and pleural effusion were more common,and digestive system symptoms were the most common non-respiratory symptoms,children <5 years old were more prone to hypoxemia(P<0.05).3.The blood picture showed normal WBC,CRP,SAA,and PCT increased to varying degrees;abnormal erythrocyte sedimentation rate could reach 78.7%,perfect throat swab culture,blood culture in this type of disease,no positive cases were found.The<5-year-old group had higher WBC,LY%,SAA,and PCT,lower NEU%,and lower Ig levels than the ≥5-year-old group;the blood picture of the group with complications was higher in NEU%,and lower in LY%(P<0.05 for all).4.The chest imaging findings of all children included 62 cases(39.5%)with lesions in the right lung,56 cases(35.7%)in both lungs,the left lung39 cases(24.8%),and the right lung were the most common lesion sites.5.There was no difference in length of hospital stay between different age groups and uncomplicated groups,and most children in this study could achieve clinical cure after about 2 weeks of hospitalization,and those with complications were more likely to be treated with glucocorticoids in the process of clinical treatment due to their severe disease(P<0.05).Conclusion:1.Mycoplasma pneumoniae lobar pneumonia is more common in children aged ≥ 5years,and it is more common in winter and autumn in the north;2.cough and Fever are the main symptoms.Children younger than 5 years old are more prone to wheezing.Hypoxemia and pleural effusion are common complications.Digestive system symptoms are the most common non-respiratory symptoms.3.The blood routine of LP caused by MP showed normal WBC,elevated SAA,CRP,and PCT to varying degrees,and children <5 years old had higher WBC count,LY%,SAA,PCT,and lower NEU% than children ≥5 years old;The NEU% of children with complications was higher than that of the group without complications,and the opposite was true for LY%.4.The prognosis of Mycoplasma pneumoniae lobar pneumonia in children is good,and after standardized treatment,most patients can achieve clinical recovery. |
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