| Purpose:To integrate the traditional advantages of traditional Chinese medicine with modern first-class medical diagnosis and treatment methods,to observe and evaluate the clinical efficacy of Guiqi Yangrong decoction combined with RPH-4 in the treatment of rectal mucosal prolapse constipation,and to put forward feasible holistic treatment plan,so as to provide reliable clinical data for the widespread use of this method in clinical practice.Material and method:Sixty patients with rectal mucosal prolapse constipation admitted to the anorectal Department of the Affiliated Hospital of Gansu University of Chinese Medicine from December 2021 to December 2022 were selected and randomly assigned into two groups,with 30 patients in each group.Treatment group: Guiqi Yangrong decoction combined with RPH-4 formula treatment,control group: RPH-4 operation combined with lactulose treatment.The main symptom score(difficulty in defecation,frequency of defecation,duration of defecation,feeling of lack of defecation,feeling of anal drop and other symptoms),fecal character score,time of first postoperative defecation,postoperative recovery(postoperative pricking pain,postoperative anal function),and recurrence 1 and 3months after the treatment were recorded and observed.The efficacy of the two groups was determined by comparing the above contents.In this study,SPSS22.0 system was used to process and analyze the data.Results:1.Comparison of general data: there was no significant difference between the treatment group and the control group(P>0.05).2.Clinical efficacy: The total effective rate of the treatment group was 100%,and that of the control group was 97.0%.The rank sum test was used,Z=3.41,P<0.05,the difference was statistically significant(P<0.05),indicating that the overall therapeutic effect of the treatment group was superior to the control group.3.Constipation main symptom score: The constipation main symptom score of the two groups after treatment was lower than that before treatment,with significant difference(P<0.05).The score of the treatment group was lower than that of the control group(P<0.05),indicating that the treatment group had more advantages in improving constipation symptoms.4.Fecal trait score: After treatment,fecal trait score decreased significantly among all groups and the difference was significant(P<0.05).Compared between groups,fecal trait score in control group was higher than that in treatment group(P<0.05).5.Comparison of postoperative recovery: The first postoperative defecation time was statistically significant,P<0.05,and the treatment group was superior to the control group.6.The pain degree of puncture 1 day after surgery(P>0.05)showed no statistical difference and was comparable.The pain degree of anal puncture 7 days after surgery was significantly different(P<0.05),indicating that the pain relief of treatment group was better than that of control group.There was no significant difference in anal function(P>0.05).7.TCM symptom score: After treatment,the scores of interdefecation period,palpitation shortness of breath,fatigue,pale face and dizziness in each group decreased(P<0.05),which was significantly better than that of the control group at 0.01 significance level.The score of treatment group was lower than that of control group(P<0.05).The treatment group was superior to the control group in terms of dry stool,defecation effort,less qi and lazy words at0.05 significant level.8.The patients were followed up 3 months after surgery: there were 0 cases of recurrence in the treatment group and 6 cases in the control group.It was found that the recurrence rate in the treatment group was significantly lower than that in the control group.Conclusion:1.Both groups of treatment can alleviate the clinical symptoms of patients,especially the improvement of TCM symptoms after treatment.Guiqi Yangrong Decoction combined with RPH-4 has outstanding effect,and is superior to RPH-4 combined with lactulose in improving the time,frequency,sensation and quality of defecation.2.In terms of postoperative pain and recurrence at 3 months follow-up,the therapeutic effect was more significant in the treatment group,indicating that Guiqi Yangrong Decoction combined with RPH-4 had a significant advantage over RPH-4 combined with lactulose in terms of long-term effect and recurrence rate.3.Combining modern medicine with traditional medicine,based on the principles of minimally invasive radical treatment and holistic treatment,Guiqi Yangrong Decoction combined with RPH-4 has reliable and outstanding efficacy,high safety,not only improving the local area but also regulating the whole.All the advantages mentioned above are the basis for further research and discussion of this research program. |
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