| Objective: Through collecting the clinical data of patients with chronic urticaria,to explore the incidence of chronic urticaria and the correlation between TCM constitution and TCM syndrome types,so as to provide new ideas for the prevention and treatment of chronic urticaria.Materials and Methods: The data were collected from 303 patients with chronic urticaria who visited the dermatology clinic of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from November 2021 to October 2022.The basic information of patients,disease severity,inducing or aggravating factors,TCM syndrome types,nine TCM constitutions and other information were collected by questionnaire,and Microsoft Excel was used for data sorting,and SPSS25.0 statistical software was used for correlation analysis.Result:1.General situation: 303 patients with CU,105 males and 198 females,with a male female ratio of 1:1.89;The minimum age of onset was 18 years old,the maximum was77 years old,141 cases(46.5%)were the most at 36-59 years old,the shortest coursewas 6 weeks,the longest was 20 years,and 238 cases(75.5%)were the most at<1 year.2.Degree of illness: degree of itching: no itching 34 cases(11.2%),mild itching 83 cases(27.4%),moderate itching 111 cases(36.6%),severe itching 75 cases(24.8%);The number of wind masses: 23 cases(7.6%)without wind masses,125 cases(41.3%)with wind masses<20,101 cases(33.3%)with wind masses 20-50,54 cases(17.8%)with wind masses>50;The frequency of wheal attack: 106 cases(35.0%)once a day,140cases(46.2%)2-3 times a week,34 cases(11.2%)2-3 times a month,23 cases(7.6%)once a few months;Duration of wheal: no23 cases(7.6%),116 cases(38.3%)<1h,130 cases(42.9%)1-12 h,34 cases(11.2%)>12h.3.Inducing or aggravating factors: 77 cases(25.4%)had no definite inducement,and 226cases(74.6%)had definite inducement,of which physical factors were the most(93 cases,30.7%),followed by food factors(62 cases,20.5%),mental factors(30 cases,9.9%),inhalation allergens(22 cases,7.2%),and drug factors(19 cases,6.3%).4.The distribution of TCM syndrome types: from high to low,86 cases of wind heat invading the exterior,77 cases of wind cold binding the exterior,48 cases of deficien cy of defence and exterior,46 cases of deficiency of both qi and blood,26 cases of gastrointestinal damp heat,20 cases of stagnation of qi and blood.There were statistica l differences between TCM syndrome types and gender,pruritus degree,inducing or a ggravating factors(P<0.05),but there were no statistical differences between TCM syn drome types and age,course of disease,number of wheals,attack frequency and durat ion(P>0.05).5.Distribution of TCM constitution(1)The distribution of single constitution: from high to low,there were 64 cases of p eaceful constitution,57 cases of yang deficiency constitution,48 cases of special const itution,30 cases of yin deficiency constitution,29 cases of qi deficiency constitution,27 cases of damp heat constitution,22 cases of qi stagnation constitution,19 cases of blood stasis constitution,and 7 cases of phlegm dampness constitution.There were stati stical differences between TCM constitution and gender,age,inducing or aggravating f actors(P<0.05),but there were no statistical differences between TCM constitution and itching degree,number of wheals,attack frequency and duration(P>0.05).(2)The distribution of mixed constitution: the most biased mixed constitution(156 cas es,51.5%),83 cases(27.4%)were single biased,38 cases(12.5%)were basically flat,T he level of calmness was the least(26 cases,8.6%).Among them,the most commonty pe of temperament is inclined temperament(11 cases),followed by qi deficiency(9 c ases).6.TCM constitution and TCM syndrome types: Yang deficiency is susceptible to wind cold binding exterior syndrome;The peaceful quality and the special quality are susceptible to wind heat,and the peaceful quality is more susceptible to wind heat,whichis more likely to offend the exterior syndrome than the natural quality;Damp heat is susceptible to gastrointestinal damp heat syndrome;Qi deficiency,yin deficiency and yang deficiency are susceptible to both qi and blood deficiency,and qi deficiency is more susceptible to both qi and blood deficiency;Qi stagnation and blood stasis are more susceptible to qi blood stasis syndrome than qi stagnation.The above results were statistically significant(P<0.05).Phlegm dampness has no statistical significance in TCM syndrome types(P>0.05).Conclusion:1.In this study,There are statistical differences between TCM syndrome types and gen der,pruritus degree,inducing or aggravating factors.2.In this study,There are statistical differences between TCM constitution and gender,age,inducing or aggravating factors.3.In this study,the quality of yang deficiency is related to the syndrome of wind and cold binding the exterior,the quality of peace and nature is related to the syndrome of wind and heat invading the exterior,the quality of dampheat is related to the syndrome of gastrointestinal damp heat,the quality of qi deficiency,yin deficiency,yang deficiency is related to the syndrome of both qi and blood deficiency,and the quality of qi stagnation and blood stasis is related to the syndromeof qi and blood stasis.4.The constitution type of traditional Chinese medicine of patients with chronic urticaria determines the formation and evolution of syndrome types.The disease is recognized through "body differentiation disease differentiation syndrome differentiation" in order to provide new ideas for clinical prevention and individualized treatment to better guide clinical practice and avoid further developnent of disease. |
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