The Study Of Diagnostic Criteria On Chronic Glomerulonephritis Kidney-Yang Deficiency Syndrome By Data Mining

Objective:1. Data mining approaches, to chronic nephritis and the literature for the study of patients with clinical, summarize common clinical manifestations, discussion on the rules and characteristics of chronic nephritis of deficiency of kidney-Yang deficiency symptoms, refining of chronic nephritis of deficiency of kidney-Yang deficiency syndrome, and general symptoms, explore ways to establish diagnostic criteria for chronic nephritis of deficiency of kidney-Yang deficiency.2. Select research object, filtered mining method in mathematics, verify wait diagnosis standard research methods and evaluation of the quality of links, explore the ideas and methods of establishing syndrome diagnostic criteria.Methods:1. Literature researchAncient medical theory, most of the modern medical and periodical literature 3. Research Group of the unified development of chronic nephritis of deficiency of kidney-Yang deficiency survey scale, each of the three most of the information collected.Ancient medical theory with correlation and cluster analysis method; modern medical and periodical literature uses correlation analysis, cluster analysis and Logistic regression analysis, model filter by Enter method and Stepwise method, evaluation using ROC curve analysis method of Logistic regression model, established with the value of primary and also permits to develop diagnostic criteria for chronic nephritis of deficiency of kidney-Yang deficiency.2. clinical researchClinical investigation of methods used, developed by the research group "chronic nephritis cases look at the table" and chronic nephritis with integrated survey scale of 251 cases of chronic nephritis (127 cases of kidney-Yang deficiency syndrome, non-124 cases of kidney-Yang deficiency syndrome) in patients with clinical symptoms. Application correlation analysis, and poly class analysis method and the Logistic regression analysis method, model filter used Enter method and Stepwise method, Logistic regression forecast model evaluation used ROC curve analysis method, data mining of method, on chronic nephritis renal Yang card of symptoms features and the distribution law for has discussion, Extracting common symptoms of kidney-Yang deficiency and chronic nephritis with primary and secondary, and general symptoms, to establish diagnostic criteria for chronic nephritis of deficiency of kidney-Yang deficiency of exploratory research.Results:1. Medical summary on partial common symptoms of kidney-Yang deficiency syndrome of chronic nephritis, including edema and water deficient, epigastric abdominal distension, waist and knee pain, fecal half congealed thin, pale lips spitting fat cold, cough, aversion to cold limbs, is satisfied that the poor eating less, difficult urination, pulse Shen, asthma, moss white slip, complexion pale white, looked dark, pulse weakness all 16.2. Medical cases some of the positive factors influencing the diagnosis of chronic nephritis and kidney-Yang deficiency symptom of a total of 9, looked pale white, looked dark, edema, nausea and vomiting, aversion to cold water deficient, cold extremities, dilute, is satisfied that a difference of half congealed in stool eating less, pale lips fat.3. Periodicals section is to impact factor for diagnosis of chronic nephritis and kidney-Yang deficiency syndrome symptoms there are 7:water deficient, edema, less fear of cold cold extremities, is satisfied that the poor food, stool half congealed rare, moss white slip, pulse Shen.4. Clinical investigation section is to the effect of spleen and kidney-Yang deficiency syndrome diagnosis factors of a total of 6, including less is satisfied that the poor food and water deficient, edema, aversion to cold cold extremities, moss white slip, pulse Shen and other symptoms.5. Under past four diagnosis symptoms description sort habits, combination data mining get symptoms frequency sort high and low, summarized, and summary and refined out chronic nephritis renal Yang card of main symptoms: including looked light white, and looked dark, and edema, and feared cold limb cold, and urine deficient, and is satisfied that difference food less, and lumbar knee pain, and stool half congealed dilute, and tongue mass light fat, and MOSS white sliding, and pulse sank, total 11, developed to this as chronic nephritis renal Yang card of diagnosis standard. Edema, aversion to cold with cold extremities and water deficient totalling 3; pale white complexion, is satisfied that the poor eating less, waist and knee pain, fecal half congealed thin, pale lips thick, moss white slip, with pulse Shen as, all 7; looked dark for general symptoms, a total of 1. Conclusion:By comparing the discovery past dynasties literature research conclusions and good clinical research conclusions anastomosis.By data mining summary and determine chronic nephritis renal Yang card of common clinical performance, including looked light white, and looked dark, and edema, and feared cold limb cold, and urine deficient, and is satisfied that difference food less, and lumbar knee pain, and stool half congealed dilute, and tongue mass light fat, and moss white sliding, and pulse sank, total 11 symptoms, developed to this as chronic nephritis renal Yang card of diagnosis standard.By comparison research, determine chronic nephritis renal Yang card of main syndrome and times syndrome, which main syndrome 3:respectively for edema, and feared cold limb cold, and urine deficient; times syndrome 7 respectively for looked light white, and is satisfied that difference food less, and lumbar knee pain, and stool half congealed dilute, and tongue mass light fat, and moss white sliding, and pulse sank; general symptoms 1:looked dark.Combination of qualitative and semi-quantitative, master of weighted integral of mode, the creation of the diagnostic criteria for chronic nephritis and kidney-Yang deficiency judgment method.Through this research, can be proved through the correct selection of objects, filtered mining method in mathematics, verify wait diagnosis standard research methods and evaluation of the quality of links and so on, initially developed chronic nephritis of deficiency of kidney-Yang deficiency syndrome diagnostic criterion applied to scientific research and clinical, features with accurate, applicable, can be widely used diagnostic criteria for TCM syndromes of various studies.