Streptozotocin-induced Diabetic Rats Renal Medullary Water Channel Protein 2 Expression And Significance

Objective:To investigate the relationship between microalbuminuria(MAU) and metabolic syndrome (MS). Methods:Four hundred and fifty-seven subjects over 30 years oldwere selected by random from health examination. They were divided into4 groups according to the latest diagnostic standard of National CholesterolEducation Program-ATP III (2001). They were control group(group A),oneitem only group(group B), incomplete MS group (group C)and completeMS group(group D).MAU were tested in every group and invested withMS. Results: The prevalence of MS in present study was 17.5%.HOMA-IR either in group C or in group D was higher than that of group A.Subjects in group D were older than those in group A and male more than female. The MS patients were 15% of all subjects in the present study. TheMAU in group D was more than that in group A (P<0.05). But it was nosignificance difference between group B, C and D. The MAU in Group Dwas an independent factor relative to systolic blood pressure and 2 hourplasma glucose in standard oral glucose tolerance test. Conclusion The diagnostic standard of NCEP-ATP III (2001) issuitable for Chinese. MAU is a factor related to MS.