| Objective: To investigate and analyze the distribution of dyslipidemia and the influencingfactors between Korean and Han nationalities in Yanbian area.Methods:①Using simple randomized principia, 3495 people of Korean nationality andHan nationality aged≥30 years from August 2005 to August 2006 in four town, Antu andTumen of Yanbian were selected. The national proportion of the original area brought intowas close, and informed consent was obtained from each subject.②Information ondemographic characteristics and lifestyle factors was collected by visiting home enquiry andhealth examination in selected community and public health center.③The surveyors werestrictly trained before investigation and the inventory content, operative procedure andmethods were standardized, and it was carried through to visit home and inquiry by standardquestionnaires.④Height, weight, waist and hip circumference, blood pressure, and thedistribution of fat were measured.⑤Blood samples were collected after 12 hours of fasting(overnight) and the lipid profiles of serum total cholesterol, triglyceride, high-densitylipoprotein cholesterol and low-density lipoprotein cholesterol were determined with thewhole automatic biochemistry analyzer in the Department of Biochemistry, ClinicalHospital of YanBian University.⑥All analyses were carried out on a PC using SPSS forWindows. Data are presented as mean values±SD. The distribution of serum lipid levelswas determined by calculating percentiles by gender and by ethnic group. Gender and ethnicdifferences for all parameters were evaluated by Tukey's multiple comparison of means in ageneral linear model. Differences of percentage were tested by the chi-squared test andu-test. Unconditional multiple logistic regression analysis was used to examine theassociation of dyslipidemia with the related risk factors such as nationality, sex, age, SBP,DBP, FBG, SUA, Hs-CRP, BMI, WC, visceral fat and body fat, and variable was selectedby the stepwise backward method in which a=0.05 as significant level of selected variableand a=0.1 as significant level of removed variable.Results: Out of 3495 cases with full results of questionnaire, anthropometry andbiochemical index measures, 1550 Korean nationality (628 males and 922 females) and1945 Han nationality (697 males and 1248 females).①The lipid profiles of TG and HDL-Chad significant ethnic differences in Men, and these of TC and HDL-C had significant ethnicdifferences in women.②The age adjusted prevalence rates of hypercholesteremia were9.61% and 14.02%(p＜0.01) in males, and 15.97% and 15.34%(p＜0.01) in females,respectively; those of hypertriglyceridemia were 37.21% and 28.96%(p＜0.01)in males, and30.90% and 28.98%(p＜0.01) in females, respectively; those of low HDL-C were 42.60%and 31.79%(p＜0.01) in males, and 52.49% and 40.44%(p＜0.01), respectively; those ofdyslipidemia were 64.74% and 56.95%(p＜0.01) in males, and 71.24% and 63.69%(p＜0.01)in females, respectively.③The distribution of the influencing factors for dyslipidemia, suchas SBP, DBP, Hs-CRP, BMI, WC, visceral fat and body fat had significant ethnic differences.④Unconditional multiple logistic regression analysis shows that the prevalenceof hypercholesteremia was correlated with sex,age,SBP,FBG,SUA,WC; and that ofhypertriglyceridemiawas correlated with nationality,DBP,FBG,SUA,Hs-CRP,WC,body fat,visceral fat,BMI; and that of low HDL-C was correlated with age,SBP,DBP,FBG,WC,body fat,visceral fat,BMI; and that of dyslipidemia was correlated withnationality,age,SBP,SUA,body fat and visceral fat.Conclusion:①The current observation shows that there were significant differences in thelipid profiles, the prevalence of dyslipidemia, and its related factors.①There weredifferences in the influencing factors for the different dyslipidemia. |
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