| Objective:to observe the clinical therapeutic effect and the content changes of Anti-oxidation factors:Superoxide-Dismutase (SOD) and Malondialdehyde (MDA) of Chronic Superficial Gastritis spleen-stomach vacuity cold(CSG-ssvc) patients by moxibustion on ginger therapy of differents moxibustion time, compare to taking medicine of ranitidine,to explore the warm effect of moxibustion on ginger for CSG-ssvc and the influence to Anti-oxidation factors.Methods:under the random,contrast and single-blind research method,84 cases who conform to the standard of CSG-ssvc were randomly divided into three groups: The therapy group A (moxibustion on ginger to the acupoints with 20 minutes) with 28 cases,the therapy group B (moxibustion on ginger to the acupoints with 40 minutes)with 28 cases and the medicine group C (taking medicine of ranitidine) with 28 cases.Moxibustion on ginger to the patients of therapy groups 1 time per day, and the patients of medicine group took ranitidine 0.15g,2 times per day. Three groups were continuous insist on 10 days for 1 treatment course,took a rest for 1 day and took 2courses by all.Treatment cycle of three groups were 23 days, follow-up office visit 1 time after 1 month later. Record the curative effects and symptoms questionnaire survey of patients on the first day, the eleventh day, the 23rd day and 1 month later. The contens of Anti-oxidation factors were taken by draw blood and test serum on the first day and the 23rd day.Result:①The total effective rates after 2 treatment courses in three groups were 85.7%for group A,89.3%for group B and 71.4%for group C.The curative effects of group B were significantly higher than group C (P<0.05).②The three groups total effective rates after follow-up office visit after 1 month were 85.7% for group A,92.8%for group B and 67.9%for group C.The group A and B had significantly long-term curative effects,and there was a statistically difference when compared to group C(P<0.01).③A,B,C groups results of the curative effects and symptoms questionnaire survey after 1 couse,2courses and 1 month later were all have significantly difference when compared to the results before treatment(P<0.01).After 1 month later the end of treatments,the results of survey had significantly difference among the three groups(P<0.01),there was a statistically difference when compared with A and C(P<0.05),there was a statistically difference when compared with B and C(P<0.01).④All the three groups contents of SOD were significantly augmented after 2 treatment courses, there was a statistically difference when compared to the contents before treatments(P<0.05).And there was a statistically difference when compared to matched the changes of group B and group A,C(P<0.05).⑤All the three groups contents of MDA were significantly decreased after 2 treatment courses,there was a statistically difference when compared to the contents before treatments (P<0.05), but there was no statistically difference compared with three groups (P<0.05).Conclusions:1.Moxibustion on ginger therapy for 20 minutes and 40 minutes and taking ranitidine were all the valid treatment of CSG-ssvc.The short-term clinical effects and the long-term follow-up effects of moxibustion on ginger for 40 minutes therapy was the best to cure CSG-ssvc. This proves that prolong the treatment time of moxibustion on ginger have the great significance to improve the clinical effect.2.It can relieve the symptoms of the CSG-ssvc patients and improve the quality of their lives with both moxibustion on ginger therapy and taking ranitidine,but there was no statistically difference by comparison.The short-term clinical effects and the long-term follow-up effects of moxibustion on ginger therapy are superior when compare with taking ranitidine.3.It can increase the contents of SOD and decrease the contents of MDA with both Moxibustion on ginger therapy and taking ranitidine. Moxibustion on ginger Therapy for 40 minutes can increase SOD contents significantly,and the results are obviously higer than Moxibustion on ginger therapy for 20 minutes group and taking ranitidine group.Confirmed that Moxibustion on ginger Therapy has benign regulative the function of Anti-oxidation factors. |