| PurposeThis paper summed up the medical records of physicians in the treatment of eczema, who is the contemporary famous TCM dermatology doctors,researched and analyzed related information in medical records, explored the law of different syndrome types of eczema in diagnosis and treatment, in order to provide reference for TCM clinical diagnosis and treatment, traditional Chinese medicine basic research, Chinese medicine preparation research and development work.MethodThis study to contemporary Chinese medicine dermatology famous doctors in the treatment of eczema of the medical records as the research object, to computer database as a platform, using TCM inheritance auxiliary software platform of V2.5, which involves the data mining methods of the rule analysis, improved mutual information method, complex system entropy clustering, unsupervised entropy and hierarchical clustering. Frequency statistical analysis of this study to collect medical records of four diagnostic information, syndrome differentiation and typing, and symptoms of different syndrome types, composition rules, potential new researchResultEczema involved a total of 148 kinds of symptoms, frequency 2332 times. Included inspection appeared 1435,63.9% of the total, and the symptoms of skin lesions appear 878 times, accounted for 37.7% of the total number of symptoms, accounted for inspection content 61.2%(878/1435); the inspection of the tongue diagnosis appeared 480 times, accounted for 20.6% of the total number of symptoms, accounted for 33.4% of the contents of the inspection; inquired contents appeared in total 635 times, accounted for 27.2% of the total number of symptoms; pulse-t aking appeared 224 times, accounted for 9.6% of the total number of symptoms.Sktin lesion of eczema with syndrome of damp-heat was characterized as erythema, papules, erosion and exudation, frequently accompanied by red tongue and constipation, where occurred mainly in in the limbs. The skin lesion of eczema with syndrome of damp-heat impairing yin was characterized as erythema, papules, erosion and exudation, frequently accompanied by infiltration, where occurred mainly in the head and neck and followed by the limbs. The skin lesion of eczema with syndrome of water retention due to hypofunction of the spleen was characterized as erythema, papules and infiltration, frequently accompanied by pachynsis and anorexia, where could occur in the whole body, mainly in the truncus and limbs. The skin lesion of eczema with syndrome of wind-dryness due to deficiency of blood was characterized as erythema and papules, frequently accompanied by squama, where occurred mainly in the limbs, head and neck. The skin lesion of eczema with syndrome of wind-dryness due to blood heat was characterized as squama, where occurred mainly in the head and neck. The skin lesion of eczema with syndrome of cold dampness was characterized as pruritus, infiltration and papules, frequently accompanied by pale tongue with thin and white fur, and deep and thready pulse.Since Sheng Dihuang had the function of nourishing yin and promoting the production of the body fluid that could restrict the impairment of yin caused by the heat-clearing and damp-drying drug, it was frequently prescribed in the treatment of eczema. And, both of Longdan Xiegan Decoction and Xijiaodihuang Decoction were modified in the treatment of eczema. Additionally, there was a collection of new candidate prescriptions for eczema with syndrome of damp-heat including Quanxie, Dangshen, Baizhi, Jiangcan, Muzei; Huangqin, Huangbai,Cangzhu, Cheqianzi, Mu tong, Zexie; Chishao, Tufuling, Boqi, Fuping, Danzhuye, Baimaogen, and Shouwuteng. The yin tonic, blood tonic, qi tonic and dampness-eliminating drugs were frequently most used in the treatment of eczema with syndrome of damp-heat impairing yin. The blood tonic, qi tonic and qi-promoting drugs made a difference in the treatment of eczema with damp-heat impairing yin. And, both of Zengye Decoction and Shashen Maidong Decoction were modified in the treatment of eczema. Additionally, there was a collection of new candidate prescriptions for eczema with syndrome of damp-heat impairing yin including Tiandong, Huangjing, Taizishen, and Mudanpi. The dampness-eliminating drugs were used the most in the treatment of eczema with syndrome of water retention due to hypo function of the spleen, followed by the drugs of replenishing qi to invigorate the spleen. And, the compatibility relationship was applied into some prescriptions, such as Pingwei Powder, Buhuanjin Zhengqi Powder, and Wuling Powder. Additionally, there was a collection of new candidate prescriptions for eczema with syndrome of water retention due to hypofunction of the spleen including Fuling, Gancao, Chao Baizhu, zhuling, Cangzhu, Mudanpi; Huangqin, Chenpi, Mudanpi, Cheqiancao, Huangbai, Jixueteng; Cangzhu, Chenpi, Mudanpi, Danggui, Shouwuteng, and Mugua. The dampness-eliminating drugs were used the most in the treatment of eczema with syndrome of wind-dryness due to deficiency of blood, followed by the drugs of replenishing qi to invigorate the spleen and the drugs of dispel wind and arrest inching. The medicine suits-Herba Schizonepetae and Radix Saposhnikoviae was the highest in the frequency of usage and confidence degree. The thought in formulating the prescriptions referred to Danggui Yinzi Decoction that could nourish yin and supplement blood as well as dispel wind to arrest inching. Additionally, there was a collection of new candidate prescriptions for eczema with syndrome of wind-dryness due to deficiency of blood including Herba Schizonepetae, Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Radix Rehmanniae Recens, Poria, and Radix Adenophorae. The drugs of cool blood including Shengdihuang, Mudanpi, and Chishao were used the most in the treatment of eczema with syndro me of wind-dryness due to blood heat, followed by the drugs of relieving itching including Baixianpi and Kushen, as well as the drugs of dispelling wind including Jingjie, Fangfeng and Chantui. Shengyang Chushi Fangfeng Decoction modified the drugs of relieving itching including Cortex Dictamni and Fructus Kochiae was often used in the treatment of eczema with syndrome of cold dampness. The drugs of supplementing qi and nourishing yin as well as promoting qi including Sheng Dihuang, Shenghuangqi and Chenpi were used the most in the treatment of eczema with syndrome of deficiency of both qi and yin, followed by the drugs of supplementing qi and nourishing yin, the drugs of invigorating the spleen, the drugs of eliminating dampness and the heat-clearing drugs. The drugs of removing the pathogenic factors on the Weifen including Jingjie, Fangfeng and Niubangzi were used the most in the treatment of eczema with syndrome of wind-heat, followed by the drugs of removing heat from the blood including Mudanpi as well as the drugs of relieving itching including Baixianpi. The drugs of stimulating circulation to end blood stasis including Sanleng, Ezhu and Hong Hua were used the most in the treatment of eczema with syndrome of toxic heat and blood stasis, followed by the drugs of removing heat from the blood including Chishao and Shengdihuang, as well as the drugs of relieving itching including Baijili. The high frequent drugs were used in the treatment of eczema with syndrome of accumulation-heat in the lung and stomach, such as Baixianpi, Sheng Dihuang and Huanglian that were categorized as drugs of hear-clearing and damp-drying, drugs of heat-clearing and fire-purging and drugs of clearing the lung and stomach. The accumulation-heat in the lung and stomach might bond with the dampness or phlegm, contributing to develop the eczema. Therefore, the accumulation-heat in the lung and stomach was the principal contradictions in the treatment of eczema with syndrome of accumulation-heat in the lung and stomach, which could be treated with modified Qingwei Powder.ConclusionIn the process of diagnosis of eczema in inspection for physicians and an important source of information, followed by interrogation, pulse. The diagnose through interrogation watching the tongueã€feeling the pulse to get the overall status of the patients are equally important as the observation of skin lesionsã€the place of occurrence. Itch is the highest frequency of different types of symptoms of eczema symptoms, which shows the itching of the differential diagnosis of eczema has important significance, at the same time itching is also the difficulty of eczema treatment. The symptom expression of the whole condition of the patients with eczema is very important for the identification of different syndrome types of eczema. Different types of eczema are using Qushi drugs, this may mean that the treatment of each stage eczema must use the dampness-eliminating drugs. Prescription regularity and candidate new prescriptions for different syndrome type of eczema are not identical. This may means that treatment based on syndrome differentiation can improve eczema treatment... |