Ropivacaine Epidural Patient-controlled Analgesia Pain-free Birth Effects And Stress Response

To study the effects of ropivacaine and patient-controlled epidural analgesia for labor analgesia and stress reaction.Methods:49 cases of active stage full-term parturients were devlded into 2 groups. 40 cases who volunteer to accept labor analgesia were selected for experimental group, 9 cases were seleted for control group from parturients who refuse labor analgesia. Experimental group was received randomily with 0. 1% ropivacaine(R) or bupivaeaine(B) respectively. Start PCA pump after 30 mm for experimental group. The drug is mixture made up of 0. 1% R or B with fentanyl. Continuous infusion is 8ml/h, bolusdose2ml, lockouttime15mm. ConductPCEA. Observeanalgesia,motor black degree,time of labor course, fetal heart rate, labor mode, postpartum, hemorrhage quantity, Apgar scores, determine PH, P02, BE-B level in the blood gas of umbilical arterial and content of corticosteroid, blood sugar, insulin in body. Results:There were significant difference (P<0.01)in the pain visual analogue scale(VAS) between experimental and control group.There were no difference(p>0.05) in VAS)between R and B Group. 0. 1% R and B didn't effect labor course and labor strength. Safe for neonate. There were no difference in modified bromage score between R and B group, but the rate of lateral episiotomy is high in B group. There were significant changes for control group on corticosteroid, blood sugar, rate of insulinand blood sugar, little change for experimental group. The change of B group was greater than R group. Conclusion: 1) It was safe and effective using 0. 1% R+1ug/mlF or0.1%B+1 ug/ml F for walking labor analgesia under PCEA. It inhibited stress effectively. (2)The motor block of ropivacaine was less than bupivaeaine. (3) The inhition of ropivacaine is better than bupivaeaine to stress response.