Effect Of Different Anesthetics Used In Labor Analgesia

Objective:To compare the effect of nalbuphine combined with ropivacaine in labor analgesia with ropivacaine alone and sufentanil citrate combined with ropivacaine.Methods:A total of 60 primiparas in Yanbian University Hospital who underwent combined lumbar-scleral analgesia were randomly selected and divided into group A,group AF,and group AN which have 20 patients in each group according to the different analgesics injected during the procedure.In group A,ropivacaine hydrochloride injection was used for epidural self-controlled analgesia.In group AF,the combination of ropivacaine hydrochloride and sufentanil citrate were used for epidural self-controlled analgesia.In the AN group,ropivacaine hydrochloride combined with nabuphine hydrochloride for epidural self-control analgesia,and the women in the three groups were injected with 0.3ml 1%ropivacaine through subarachnoid space before epidural self-control analgesia.The Visual Analog Scale(VAS)and Modified Bromage Score(MBS)of each time node before labor analgesia operation,10min,30min,60min after operation,and at the time of full hysterectomy were performed according to the maternal feedback.The changes of SBP,DBP and HR were monitored and recorded at 10min,30min and 60min after labor analgesia,as well as the collection of maternal dizziness,nausea and vomiting,skin itching,urinary retention and other adverse conditions occurred time,collate the data and make a comparative analysis to draw conclusions.The final results will provide a good reference for drug selection of labor analgesia technology.Result:1.There was no significant difference in age,height,and weight between the three groups of maternal(P>0.05).2.There was no significant difference in VAS score between the three groups before labor analgesia(P>0.05).VAS scores of parturient women in group AN and group AF were significantly lower than those in group A(P<0.05)at l0min,30min and 60min after analgesia,but there was no significant difference between AN group and AF group(P>0.05).3.The incidence of adverse reactions such as nausea and vomiting,urinary retention,and pruritus in the group AF was higher than those in group AN and group A(P<0.05),and there was no statistically significant difference between the group AN and group A in adverse reactions(P>0.05).4.There was no statistically significant difference in SBP at 10min,30min,and 60min after labor analgesia operation in the three groups(P>0.05),and no statistically significant difference in DBP at 10min,30min,and 60min after labor analgesia operation in the three groups(P>0.05).The HR of the three groups of women at 30min and 60min after labor analgesia were lower than those at 10min after labor analgesia(P<0.05).5.None of the 60 pregnant women who underwent labor analgesia showed motor nerve block so that all the MBS score was 0.Conclusion:In the application of labor analgesia drugs,both nalbuphine combined with ropivacaine and sufentanil citrate combined with ropivacaine had good analgesic effects,and the circulation was stable.However,the incidence of adverse reactions in combination with ropivacaine was significantly lower than sufentanil citrate,which was worthy of clinical application.