Observation Of The Clinical Efficacy Of. And Drop The Capsules In Treatment Of Reflux Esophagitis (mixed Cold And Heat Syndrome)

This study includes mainly two parts: theoretical research and clinicalresearch.In the part of theoretical research, the author sums up and analyses thepathogenic factor studying the diagnosis and pathogenesis in historical documentsof Reflux Esophagitis(RE), and sums up the therapeutic methods of RE in recentyears so as to look for a better way.In the clinical research, 60 patients with reflux esophagitis diagnosed byendoscopy were randomly divided into two groups. The treatment group (n=30)took hejiang capsules 3 ones bid; the control group (n=30) received only cimitidinomeprazole 20mg bid; all the cases were treated for 8 weeps. The symptoms andgastroscopic feature were observed and recorded. In the treatment group, 10 casesrecovered, 15 cases significantly improved, 4 cases improved, 1 ineffectual case.The total effective rate of the treatment group is 96.7%. In the control group, 9cases recovered, 13 cases significantly improved, 6 cases improved, 2 ineffectualcases. The total effective rate of the control group is 93.3%. After 8weekstreatment, all the symptoms are improved significantly in both two groups. Themajor symptoms of reflux acid are improved more significantly in control groupthan treatment group.But in the treatment roup, the minor symptoms of eructationmouth bitter and diarrhea symptoms are improved significantly than in the controlgroup.The above scientific researches indicate:1 Eating and emotion are two main aspects of the causes of RE.2 The two primary symptoms of semiological characteristics are heartburnacid regurgitation. And a patient of RE often shows red or dark red tongue withyellow greasy or thin coating, taut or smooth pulse.3 The chief pathogenesis is syndrome of combined with cold and heat anddysfunctional of Qi. The main treating method is regulate the cold and heat, andregulate the converse of Qi.4 The finding of the present study indicated that decoction for coordinatingthe function of the liver and the stomach is obviously superior to that of improvingthe parts of RE symptoms and efficacy of decreasing the recurrence rate exceedsthat of omeprazole.5 The mechanism shows as follows:a)improving clinical symptoms,regulating whole function of the body.b)promoting the gastric and esophagus emptying and accelerate regeneration and recondition of tissue of esophagus,strengthen the defensive function of counteracting reflux.c)constrict secreting ofstomach acid and bile counteracing assailant factor.