| Objective:With the ageing of society is becoming increasingly serious,osteoarthritis of the knee has become a global public health problem is caused because of arthritis and its complications have serious impact on the quality of life of older persons.Osteoarthritis of the knee effective prevention and treatment has become an urgent task,the study of the purposes of scientific research to serve the community for osteoarthritis of the knee treatment to find a safe,convenient and effective way to continue.Through Chinese and Western Medicine Clinical comparison of the combination of research,comparison of Chinese medicine that is triple governance practices plucked string,functional physical training,Chinese medicine Steaming or knee joint intraarticular injection of sodium hyaluronate for osteoarthritis of the knee clinical efficacy and safety.Methods:All of the patients were from Hubei Province Chinese medicine hospitals and outpatient orthopaedic wards,since March 2006 to March 2008,according to cases included in the standard case and exclusion criteria.120 Knee Osteoarthritis patients were randomized into Treatment Group and Control randomly.For Treatment Group,cases were treated with the three united remedy of TCM external therapy as:Chinese naprapathy,functional exercise, herbs fumigating for Knee Osteoarthritis,for 5 weeks a course.For Control Group,cases were treated with the intra-articular sodium hyaluronic acid injections with 2ml per time,1 time per week,for 5 weeks a course.All cases were selected to the basic conditions of registration,in accordance with the patient's clinical symptoms and type Syndrome score, followed by the tests.Patients have to be selected after a month of the treatment,there have been rigorous and regular follow-up and review.After the treatment,and again after treatment on the clinical symptoms score and efficacy evaluation and review liver and kidney functions and biochemical indicators,follow-up time from August to December, recording and comparison of the treatment group and control group in patients with symptoms of knee improve the situation,SPSS13.0 data using statistical software for statistical analysis. Results:Treatment group and the control group after treatment indicators have improved significantly,the difference between before and after treatment(P＜0.01).The treatment group for knee pain,function,activity,strength,flexion deformity and instability improvement compared with the control group there was no significant difference(P＞0.05).Two cases after treatment compared to the long-term effect was no significant difference(P＞0.05).Two cases of drug safety after treatment compared to the difference was not statistically significant(P＞0.05).Two medical treatment after the onset time difference,was not significant(P＞0.05).Severity of the treatment group compared with the effect of:the treatment group mild and severe,moderate and severe effects are very significant differences(P＜0.01),mild to moderate effects and there was no significant difference(P＞0.05).Treatment group and the length of the course of the comparison:in the treatment group compared efficacy of different length of the course there was no significant difference(P＞0.05).Clinical stages of the treatment group compared with the effect of:in the treatment group compared different clinical stages of no significant difference(P＞0.05).Conclusion:Chinese medicine governance practices plucked string triple that of functional physical training,Chinese medicine Steaming on the treatment of knee osteoarthritis disease is effective with the use of sodium hyaluronate considerable effect,and relatively low cost, it is worth clinical application.However,the number of cases in this group slightly less, to reflect the results of the accuracy and comprehensiveness,there are some limitations. |
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