Pap Treatment Of Osteoarthritis Of The Experimental Research

Purpose: To study effective function mechanism of Pilose antler peptide on OAMethod: Twenty fours New Zealand's rabbits, Male and female fifty-fifty, Divide them into 8 set averagely ,3 per set. The animal model of OA was induced by Hulth's method in animals of experiment group, Another one don't operation. Make a group of model weekly. From ninth, the cycle begins, we kill a group of rabbit weekly. Make and cultivate the OC, and we divide them into 5 set. Be respectively: control group,model group,VAPs6μg/ML group,VAPs12μg/ML group and VAPs24μg/ML group. Part for add the chemical reagent. At last we pass fixed method to check the results.Result: Velvet antler polypeptides is not benefit to Osteoarthritis Chondrocytes's Breed. Velvet antler polypeptides can improve the GAG andⅡCol'proportions, which in the Osteoarthritis Chondrocytes.Conclusion: Chondrocytes is the basis of ECM. If the Chondrocyte can't work regularly., Osteoarthritis will be Happened. So that, Chondrocytes is important to the Osteoarthritis. This experiment can show that Velvet antler polypeptides is not benefit to Osteoarthritis Chondrocytes's Breed. Velvet antler polypeptides can improve the GAG andⅡCol'proportions, which in the Osteoarthritis Chondrocytes.