| Understanding of the human body to Nature is an important feature of Chinese medicine is one of the ancients in the long process of clinical practice and theoretical speculation formed. "Man" theory of nature that are closely related with the organic whole, people living in nature, but also inevitably suffering from the impact of the natural world. TCM viscera that constitute the human body is the five internal organs as the center of the organic whole, the five internal organs function in the human body must also closely linked with nature, that "the five internal organs seasonal. "1. ObjectiveThe study of literature and experimental studies to "Heart blood," as the starting Exploration of the cardiovascular activities adapt to seasonal changes of the natural environment; to explore deeper into the Chinese "Man", "four seasons five internal organs, yin and yang theory."2. Method2.1 Theoretical Discussion"Heart to be the summer" theory that the mind should be connected with the summer, the heart qi wang in the summer, the main blood vessels in the summer of heart function in a dominant position; while in other seasons, the physiological function of heart should be changed from time to time, in a subordinate position.2.2 Experimental Study2.2.1 Experimental DesignPineal secretion of melatonin has a regulatory role of the body, melatonin secretion is closely related to changes in illumination; plasma TXB2,6-Keto-PGFla content changes and the blood is closely related to the state, The experiment blocked by pinealectomy of light signal transduction observed in plasma TXB2,6-Keto-PGFla levels in winter and summer seasons, and to explain its "Heart blood" related.2.2.2 Experimental animalsAnimals:Healthy SD rats, male, weight 80-100g. Were randomly divided into normal group, the pineal gland removal surgery group,pseudo-operation group, normal feeding one week to adapt to the environment. Model group, sham animals were solstices 5 weeks before the implementation of Pinealectomy and sham surgery, and physiology in animals kept under the same conditions to the summer solstice and winter solstice, abdominal aortic blood.2.2.3 DetectionHeart rate, blood pressure was detected with a blood pressure, TXB2,6-Keto-PGFla levels detected by radioimmunoassay.2.2.4 AnalysisSAS9.0 statistical analysis software used to process data. Each set of data are used mean±standard deviation (x±s); the season group and winter and summer among the three groups are the single factor analysis of variance (One-Way ANOVA) test (with P<0.05 as significantly different P<0.01 for the difference is significant).2.2.5 Experimental resultsIn physiological conditions, plasma TXB2 content in summer and winter seasons comparison, the changes found in winter than in summer, and the difference was significant (P<0.01); 6-Keto-PGFla content showed the trend of the summer than in winter, and the difference very significant (P<0.01). Through the summer and winter plasma TXB2,6-Keto-PGFla content ratio analysis, found that:under normal physiological conditions, the winter of T/K ratio was significantly higher than the summer solstice T/K ratio.3 Conclusion3.1 TXB2/6-keto-PGF1a content changes in the winter and summer is the "Heart blood," embodied function in biological3.2 TXB2/6-keto-PGF1αthe content and the rhythm of melatonin in regulating... |
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