| Stress ulcer (SU), also known as acute erosive gastritis (acute erosive-hemorrhagic gastritis), is a form of inflammatory erosions, superficial ulceration and gastrointestinal bleeding as the main feature of acute stress-induced gastric mucosal lesions. Mainly involves mucosa to gastric erosion is characterized by multiple, but the severity of gastric inflammation was absent. The symptoms were mostly caused by certain diseases or complications of factors, clinical manifestations were vomiting blood, black stool or no obvious symptoms. The occurrence of this disease is often easy to increase the primary disease, or cause bleeding; clinical symptoms are not obvious, easy to miss the opportunity to lead the treatment of exacerbations, severely affected the life of patients and quality of life.The disease belongs to Chinese medicine, "stomach", "fullness" and other areas in recent years, Chinese medicine in the prevention and treatment of stress ulcer aspects of a large number of experimental studies and clinical research, and made some progress. Studies have shown that acupuncture can not only promote the local ulcer healing, but also effectively regulate the functional status of the entire body, from the various promote ulcer healing, reduce recurrence.Acupuncture is clear the meridians, yin and yang, and uphold the role. Recent studies have shown that acupuncture can clear the meridians, transfer gas, such as rule of God Effect, neuroendocrine-immune network in the release of neurotransmitters and hormones to increase body resistance to stress damage the ability to control it is acupuncture stress one of the mechanisms of disease. Acupuncture has a healthy two-way regulation, through multi-level, multi-channel, multi-tool to adjust the body to achieve comprehensive protection of gastric mucosa aim to achieve the role of stress ulcertreatment.Purpose:The subject of stress ulcer (SU) prevention and treatment to acupuncture results for the study, in order to widely distributed in the brain-gut axis has significant brain-derived neurotrophic factor (BDNF) as an important research target is to investigate acupuncture on SU Rats and control mechanism for the prevention and treatment of clinical SU to provide a basis for animal experiments.The study:1 Acupuncture on gastric motility in rats with stress ulcer and the impact of dietaryPurpose of this study is to observe the dynamics SU gastric conditions, diet changes in the determination of toner to promote the percentage of rats measured daily food intake; to evaluate acupuncture on gastric motility in rats and the SU diet situation. 2 Effects of acupuncture on gastric stress ulcer pathology morphologyThe experimental stress ulcer in rats by gastric histopathological observation, analysis of stress ulcer in rats reliability of the model to study acupuncture on stress ulcer in rats.3 Acupuncture on stress ulcer in the rat hippocampus BDNF contentIn this study tries to analyze the rat brain BDNF levels in the changes of SU observed on gastrointestinal function and brain-related effects, evaluation of prevention effects of acupuncture on SU.Results:1 Food intake:the treatment group and model group A compared,# P<0.05, significantly different; prevention group compared with the model group B,** P<0.01, very significant difference.2 The percentage of gastrointestinal motility:the model group B control and prevention group,* P<0.05, significantly different.3 Ulcer damage index score:the treatment group and model group A compared,# # P<0.05, very significant difference; prevention of group B compared with the model group,** P<0.01, very significant difference.4 BDNF content:the treatment group and model group A compared,# P<0.05, significantly different; prevention group compared with the model group B,** P<0.01, very significant difference.Conclusion:The results showed that acupuncture can effectively combat stress ulcer, and may pass on the brain-gut-related intervention, regulation of gastrointestinal function, as further research provides a theoretical basis. |
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