| Objective:This topic proposed by observation in western medicine cure (control blood sugar, improve neuropathy) and the Chinese medicine external treatment (shu huo powder local bubble wash treatment) combined with early lower extremity arterial disease Of diabetic patient(LEADDP) before and after treatment symptoms, signs of change, laboratory results, preliminary discussion to change chaotic detoxification, dredging of traditional Chinese medicine preparation for treatment-easy to improve shu huo powder early LEADDP role and its possible mechanism, and draw objective shu huo powder local soak them early LEADDP analyze the effect of treatment.Methods:The forward-looking random single-blind contrast method was utilized in this clinical research. We set up strict diagnostic standard, into the standard, eliminate the standard for the screening of cases, the patients were60cases, simple random distribution as30patients in the trial,30patients in the control group. Patients in the control group based on the combined with shu huo powder bubble wash limb, bubble washed2times per day,15days for a period of treatment, continuous treatment2treatment; And control group insulin (door winter insulin30) to control blood sugar, lipoic acid injection improve nerve damage, and to plain boiled water soak them limb, bubble washed2times per day,15days for a period of treatment, continuous treatment2treatment. Design observation table records before and after test patients symptoms improved, laboratory data change, and adverse events, adverse reactions to clinical data to a database of the data management, SPSS and package material of statistics, statistical method classification material inspection, grade material with X2with Kruskal-Wallis (correct), many groups with ANOVA is mean differences (ANOVA), etc.Results:The treatment group patients after shu huo powder scattered bubble wash treatment two course, treatment of the curative effect of the total effective rate of93.8%, whereas the control effect of the total effective rate was56.8%; The statistics processing, the treatment group compared with the control, both significant difference (P<0.01). This shows that, in insulin (door winter insulin30) to control blood sugar, lipoic acid injection improve neuropathy treatment based on, try to live comfortable soak them powder of limb clinical symptoms improved obviously better than the control group.In the treatment of lower limb feel abnormal aspects, the treatment group and control group were significantly the curative effect, the effectiveness of the control group was as high as70%, considering this is the role of lipoic acid effect; And the effectiveness of treatment group was as high as100%, compared with the control group, far higher than those in the control group (70%) of the efficient, a statistically significant (P<0.01), this shows that shu huo powder with independent alpha-lipoic acid scattered in the improvement of lower extremity arterial disease Of diabetic patient caused by the neuropathy roleIn the treatment of lower limb skin pigmentation, intermittent lameness, lower limbs, foot back pulses weakened, etc, the treatment group in skin pigmentation in the lower extremities of efficiency is as high as87.5%, intermittent claudication efficient reaches as high as88.2%, the pain in the lower extremities, efficient reaches as high as87.5%, foot pulses to back down as much as86.7%of the efficient; And the control group in skin pigmentation in the lower extremities, the efficient only44.4%of intermittent claudication efficient only38.9%, lower limbs only46.7%effective, the back foot pulses weakened only37.5%efficient; This shows that shu huo powder in the treatment of lower extremity arterial disease Of diabetic caused in the symptoms of skin pigmentation, intermittent lameness, lower limbs, and foot back pulses abate, with the exact clinical curative effect.Conclusion:Shu huo powder in early lower extremity arterial disease Of diabetic improved clinical symptoms of cardiovascular patients feel of the lower limbs, lower limb abnormalities in skin pigmentation, intermittent claudication, lower limb pain and foot back pulses abate.the results were better than control group, and no bad reaction. This shows that shu huo powder has good effect to improve lower extremity arterial disease Of diabetic, is more easy to use, inexpensive and efficacy is obvious and other characteristics, it is worth of application promotion. This shows that shu huo powder clinical symptoms of lower limb vascular disease has or the improving function of, especially in improving Lower limb feel abnormal is unusual advantages; is more easy to use, inexpensive and efficacy is obvious and other characteristics, it is worth of application promotion. |