| Objective:To observe the clinical efficacy of self-designed Chinese medicinalformulae in treating hyperlipidemia and its safety.Methods:Sixty patients ofPhlegm-Damp Syndrome in Hyperlipidemia were divided into therapeutic group (30cases)and control group (30cases) randomly. The patients of therapeutic group were receivedChinese medicine, each medicinal preparation water will fry two times will take juice200ml respectively, after the mix, altogether400ml sooner or later to divide. The patientsof control group were given Zocor(simvastatin), each one (20mg), once a day. The courseof treatment lasted8weeks.The scores of TCM syndrome index and the changes oflaboratory parameters were observed and compared before and after treatment.Results:1.The comparison of TCM points between two groups before and aftertreatment:After treatment,TCM points of Chinese medicine symptoms are significantlylower than before treatment,and there is statistically significant difference (P<0.01).2.Clinical Comparison of two groups before and after treatment: After treatment,the totaleffective rate is86.67%(treatment group),83.33%(control group),and there is nostatistically significant difference (P>0.05),which reveals two groups have the sametreatment.3.The comparison of blood lipids in Two groups before and after treatment:thetwo groups after treatment in patients with TC, TG, LDL-C, are lower than those beforetherapy and HDL-C has increased. There is statistically significant In the same group(P<0.05).In lower plasma viscosity and whole blood viscosity, The treatment group hadsignificant efficacy than the control,compared the two groups,there is significant difference(P<0.05),which shows the treatment group has good effect in lower plasma viscosity and whole blood viscosity. However, there were no significant differences of thetriglycerides (TG),cholestrol(TC) and low density lipoprotein(LDL) between the twogroups (P>0.05). Conclusion: Through clinical observation, self-designed Chinesemedicinal formulae can ease and improves the clinical symptoms, regulate the lipidmetabolism. preliminary confirmed the the method of hyperlipidemia treatment (Qistagnation and blood stasis) is safe and effective. |