Glycolipids Flat Intervention Transresistance Phlegm And Blood Stasis Type Of Clinical Study Of The Metabolic Syndrome

Metabolic syndrome(MS) is a condition which is associated with increase cardiovascu-lar disease. Diabetes and cardiovascular disease are its main clinical consequences. In recent years, MS has become a major disease affecting human health and increased year by year. Therefore, detecting and diagnosing MS in the early stages, exploring the pathogenesis and seeking effective prevention is the current topic focus on for medical field.This paper is divided into two parts, the first part is traditional Chinese and Western medicine literature review, the second one is clinical research.The Chinese Medicine literature review is about the recent progress of MS from disease name, etiology, pathogenesis and syndrome differentiation and treatment, while the other one summarizes the modern medicine research progress of the disease, including the epidemiology,pathogenesis,diagnosis standard and prevention and treatment methods.Clinical research part:Objective:To objectively evaluate clinical efficacy for tangzhiping on phlegm and blood stasis syndrome of MS patient;Methods:By the randomized,control studies,62cases of MS patients who met the research standards were divided into two groupsrthe TCM treatment group (31patients)and the control group(31patients),MS knowledge education were given to the control group,with taking metformin tablets,while the same measures to TCM treatment group,besides taking tangzhiping particles. Fasting blood glucose (FPG),2hours plasma glucose (2hPG),glycosylated hemoglobin(HbAlc), fasting insulin (FINS),homeostasis model assessment of insulin resistance (HOMA-IR), blood pressure (SBP, DBP),total cholesterol(TC), low density lipoprotein(LDL), highdensity lipoprotein(HDL), triglyceride(TG), waist circumference(WC), weight, body mass index(BMI) and the clinical symptoms changes were compared between two groups after three months; Results:Tangzhiping can effectively improve the clinical symptoms of MS patients,the total efficiency of treatments groups on TCM syndrome was as high as86.67%,which was higher than that of the control group(P<0.05),TCM treatment group can reduce FPG,2hPG,HbAlc, FINS,reduce TC, TG, LDL, decrease systolic blood pressure,reduce weight, improve insulin resistance;especially in blood-lipid regulation, systolic blood pressure decreased, clinical symptoms improvement were significantly better than the control group (P<0.05)).During the studies,the TCM treatment group did not show any adverse reactions and side effects;Conclusion:Tangzhiping particles can significantly regulate glucose-lipid disorder on MS patients belongs to phlegm and blood stasis syndrome,it is a safe and effective compound.