| Atopic dermatitis (AD) is a kind of genetic and allergic related immune-mediated skin disease, with characteristics of chronic, pruritic, recurrent and inflammatory. It is often accompanied with diseases such as asthma and allergic rhinitis. Its incidence rate is rising year by year. The main symptom of atopic dermatitis is pruritus, which greatly affects the patients and their family life quality, and also to the physical and mental health of patients.At present, the treatments of the disease are mainly using drugs, photochemical and psychological counseling, etc. The western medicine can only control the symptoms of the disease, yet long-term usage of drugs would lead to various adverse reactions.Acupuncture may improve patients’body functional status. Researches showed that pricking blood therapy can improve the immune system, prevent excessive inflammation reaction and help repair the recovery of body cells and its function. This study aims to observe the clinical evaluation of pricking blood therapy treating AD, to look for a safe and effective treatment for the disease. Meanwhile, we may also extend the application of pricking blood therapy for different diseases.This paper is divided into literature review and clinical research.The literature reviewThe first article expounded the pathogenesis of AD, also the general situation of diagnosis and treatments of the past10years. The second article analyzed the etiology of Traditional Chinese medicine (TCM) of the disease, then retrospected the research progress of its syndrome differentiation and treatments of TCM.The clinical researchObjective:To observe the efficacy of pricking blood therapy in treating AD, by analyzing the blood serum total IgE and eosinophils (EOS) count of change before and after the treatment.Methods:63cases of as damp-heat type AD, were randomly divided into observation group with32cases and control group with31cases. Both groups required a foundation treatment, additionally the observation group had pricking blood therapy using three-edged needle in the chosen acupoints and severe itching parts once a week, where the control group took the loratadine tablets10mg orally once a day. Two groups were treated in a total of4weeks. Patients’clinical symptoms, serum total IgE level and blood eosinophil (EOS) count of change and the safeness were observed before and after treatment. Finally, the statistical analysis of its clinical efficacy was made.Results:(1) There are no significant difference (P>0.05) in the gender, age, duration and state of illness, and VAS integral, EASI integral, affected area, TCM symptoms points, the serum total IgE level and blood cells EOS count etc. (2) The observation group and control group in clinical effect comparing is no statistical differences (P>0.05), shows that both treatments have the same curative effect. But the cure and significant efficiency rate of the observation group (67.7%) is appearently higher than the control group (37.9%).(3) Pricking blood therapy can greatly improve clinical symptoms, the serum total IgE levels and blood EOS count, but in the improvement of symptoms pruritus, observation group is significantly better than drugs group (P<0.05). The other symptoms showed the same effectiveness as the control group(P>0.05).(4) Both treatments can significantly improve TCM symptoms, yet the total effect of the observation group is better than the control group (P<0.05).(5) In the course of the study, no serious adverse reactions occured.Conclusion:Pricking blood therapy is a safe and effective method treating damp-heat type atopic dermatitis, especially it showed a remarkable improvement for relieving itchiness. Therefore, pricking blood therapy is worth of promoted in treating AD. |
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