The Study Of The Relationship Between Carotid Atherosclerosis And Blood Lipid Levels In Patients With Cerebral Infarction In Yi Populations

PurposeDetect the carotid atherosclerosis(CAS) and blood lipid levels in patients with cerebral infarction (CI) in yi population,study the relationship between CAS and blood lipid level,and their effect in CI.MethodsWe analyzed the color dopplor flow imaging(CDFI) data of carotidarteries of50patients with cerebral infarction in yi populations from People’s Hospital of Chuxiong, and evaluated the levels of blood lipids,mainly includes total cholesterol(TC), triglyceide(TG),low density lipoprotein-cholesterol(LDL-C) and high density lipoprotein-cholesterol(HDL-C).compare contrast and correlation analysis.Resultsl.The relationship with CAS and blood lipid levels:the level of LDL-C in the carotid plaque group(4.19±1.35mmol/L)was significantly higher than the non-atherosclerosis plaque group(2.90±0.81mmol/L), Comparison between the two groups are statistically significant (p<0.01).; the level of HDL-C in the carotid plaque group (0.92±0.37mmol/L) was significantly lower than the patients the non-atherosclerosis plaque group1.67±0.12mmol/L. Comparison between the two groups are statistically significant The differences among othere components of lipids were not significant.2.The relationship between the stability of carotid plaque and blood lipid levels:The level of LDL-C in the unstable plaque group4.69±1.16mmol/L was significantly higher than the stable plaque group3.37±1.38mmol/L (P<0.01), the level of HDL-C in the unstable plaque group0.68±0.37mmol/L was significantly lower than the stable plaque group0.98±0.36mmol/L (P<0.01); The differences among othere components of lipids were not significant.3.The relationship with the formation of carotid plaque and dyslipidemia:use the Pearson product-moment correlation coefficient analysis the correlation between dyslipidemia and the formation of carotid plaque,high LDL-C and low HDL-C have correlation with plaque formation.the relationship between high LDL-C and plaque formation was stronger than low HDL-C;we also found the rate of patients with dyslipidemia in the plaque group was higer than the non-atherosclerosis plaque group, LDL-C and HDL-C between the two groups are significant, The differences among othere components of lipids were not significant;4. Put the significant factors into binary logistic regression analysis, we found LDL-C and HDL-C were the risk factors of CAS.Conclusion1.CI is closely related with CAS.the CDFI play a very important role in evaluating the risk of atherosclerosis which was the etiology of patients with Cl:2.CAS and the stability of carotid plaque was related with high LDL-C and low HDL-C;3The formation of carotid plaque are related with high LDL-C and low HDL-C in the patients with CI in yi population, the relationship between high LDL-C and plaque formation was stronger than low HDL-C; we found the rate of patients with dyslipidemia in the carotid plaque group was higer than the non-atherosclerosis plaque group, and high LDL-C and low HDL-C have relationship with CAS in the CI patient who also suffer dyslipidemia;4High LDL-C and low HDL-C were the risk factors of CAS in the patients with CI in yi population.