A Comparative Study On Immediate Analgesic Effect Of Acupuncture And Moxibustion Sanyinjiao On The Patients Of Primary Dysmenorrhea Of Congealing Cold-Damp

Objective: Primary dysmenorrhea(Primary Dysmenorrhea, PD) is also called functional dysmenorrhea. It refers to the unsubstantial pathology of female reproductive organs, whose main symptoms are hypogastric spasm and periodic pain in the menstrual period(before or after menstruation). As female common disease and frequently-occurring disease, it usually happens to adolescent girls and unmarried young females. According to survey, the female with PD account for 53.2% of the females with dysmenorrhea and it exerts a serious impact on women’s health,life, work and study. Therefore,it is particularly important to seek a good curative therapeutic methord which is safety with non-toxic side effects,and can relieve pain quickly.At present, there are many treatments for the disease in Chinese traditional and Western medicine. Western medicine mainly elect prostaglandin synthetase inhibitors,non steroidalanti-inflammatory drugs, contraceptives and other drugs for treatment, which can achieve certain effect. But the treatment entails high drug dependence,serious side effects,high recurrence rate and poor long-term effect. But Chinese mediceine for primary dysmenorrhea achieves blatant progress, especially the acupuncture treatment with blatant advantage. For years, my supervisor has been devoted to the clinical study of acupuncture treatment for primary dysmenorrhea. Therefore under the direction of Professor Hong Li SUN and Professor Yan Fen SHE, this thesis will explore the functions of acupuncture and moxibustion on primary dysmenorrhea with the patients of primary dysmenorrhea syndrome of cold damp stagnation as the research object. Via comparing the different function of acupuncture and moxibustion on Sanyinjiao, this thesis will draw the difference of immediate analgesic effect of two different stimulating methods on dysmenorrhea patients namely the difference of immediate analgesic.By observing primary dysmenorrhea patients’ symptom scores before and after treatment, pain visual analogue scale(VAS-P),anxiety visual analog scale(VAS-A) and other index changes as well as time of analgesic reaction,this thesis will explore the difference of immediate analgesic effect of acupuncture and moxibustion on Sanyinjiao,to expect to provide evidence to choose the best time of immediate analgesic for the clinical treatment of primary dysmenorrhea.Methods: 60 patients with primary dysmenorrhea are all from Hebei Medical College from March 2013 to August 2014. In line with standard of diagnosis and admission, all patients divided into 2 groups at random, namely 30 patients for acupuncture and 30 patients for moxibustion. The first day of dysmenorrhea and the VAS-P ≥ 40 mm, the patients will receive treatment. Acupuncture groups: acupuncture patients at bilateral Sanyinjiao acupuncture with 0.3×40mm disposable sterile needles piercing 1-1.2 inch for once. Manipulate needles for 30 seconds every 10 minutes and retain needles for 30 minutes; moxibustion group: Fix moxa box at patients’ bilateral Sanyinjiao(single hole aims at the acupoint). Ignite moxa in the moxa box adjust the distance from patient’s skin with the warm and red skin as standard. The process lasts 30 minutes. The two groups were operated by the operater. Then the recorder should observe and note the symptom score, VAS score, and analgesic reaction time of the patient from acupuncture and moxibustion group before and after treatment. Finally the arrangement and analysis of the all data rely on SPSS13.0 statistics software.Result:1 The comparison of patient’s background: the ages, the stage of disease, the pathography and etc. are almost equal, the difference is not significant(P>0.05) in statics and is comparable.2 The comparison of analgesic reaction time between acupuncture group and moxibustion group: compared with moxibustion group, acupuncture can relieve pain sooner, the difference was statistically significant(P<0.01).3 The comparison of pain visual analogue scores(VAS-P) between acupuncture group and moxibustion group: before treatment, VAS-P score is balanced and the difference was not significant(P>0.05), therefore the experiment is comparable.① acupuncture group: compared with the before treatment, the patients’ VAS-P scores decline significantly very after treatment and 10 minutes after treatment, the difference is statistically significant(P<0.01); compared with the very after treatment, 10 minutes after treatment,the patients’ VAS-P scores still decline significantly and the difference is very significant(P<0.01).② moxibustion group: compared with the before treatment, the patients’ VAS-P scores decline significantly very after treatment and 10 minutes after treatment, the difference is statistically significant(P<0.01); compared with the very after treatment, 10 minutes after treatment,the patients’ VAS-P scores still decline significantly and the difference is very significant(P<0.01).③ two groups: the VAS-P of both groups are similar the very after treatment and 10 minutes after treatment, the difference is not significant(P>0.05); Compared with before treatment,VAS-P decrease significantly very after treatment and 10 minutes after treatment for both acupuncture and moxibustion group.4 The comparison of anxiety visual analog scores(VAS-A) between acupuncture group and moxibustion group before and after treatment: before treatment,VAS-A score is balanced and the difference was not significant(P>0.05), therefore the experiment is comparable.① acupuncture group: compared with the before treatment, the patients’ VAS-A scores decline significantly very after treatment and 10 minutes after treatment, the difference is statistically significant(P<0.01); compared with the very after treatment, 10 minutes after treatment,the patients’ VAS-A scores still decline significantly and the difference is very significant(P<0.01).② compared with the before treatment, the patients’ VAS-A scores decline significantly very after treatment and 10 minutes after treatment, the difference is statistically significant(P<0.01); compared with the very after treatment, 10 minutes after treatment,the patients’ VAS-A scores still decline significantly and the difference is very significant(P<0.01).③ two groups: the VAS-A of both groups are similar the very after treatment and 10 minutes after treatment, the difference is not significant(P>0.05); Compared with before treatment, VAS-A decrease significantly very after treatment and 10 minutes after treatment for both acupuncture and moxibustion group.5 The comparison of symptom scores between acupuncture group and moxibustion group before and after treatment: before treatment, the symptom scores are balanced and the difference was not significant(P>0.05),therefore the experiment is comparabl.① acupuncture group: compared with before treatment,the patients’ symptom scores decline significantly, the difference is statistically significant(P<0.01).② moxibustion group: compared with before treatment,the patients’ symptom scores decline significantly, the difference is statistically significant(P<0.01).③ between the two groups: symptom score comparison between the two groups are similar after treatment, the difference is not significant(P>0.05). Symptom scores decrease significantly after treatment after treatment for both acupuncture and moxibustion group.6 Safety Comparison: In the process of implementation, the patients of moxibustion group have no discomfort, scald and other situations and all patients belong to GradeⅠof safety evaluation. There were 2 cases of adverse reactions in the acupuncture group. 2 patients have gastrointestinal reaction(nausea) and recover spontaneously without treatment. All patients belong to gradeⅡof safety evaluation. In the comparison of the adverse reaction rate of both groups,there is no significant difference(P>0.05).Conclusion:1 Acupuncture and moxibustion can reduce patients’ pain visual analog scale and stop their pain quickly. But acupuncture has a better result than moxibustion. It demonstrates that two treatments have a better analgesic function which can relieve the pain and shorten the time of pain. And the analgesic effect of acupuncture is faster and stronger than that of moxibustuin.2 Acupuncture and moxibustion can both reduce patients’ anxiety visual analog scale. But acupuncture has a better result than moxibustion. It indicates that the two treatments can regulate autonomic nervous function, improve the body’s stress ability so as to improve anxiety. And the effect of acupuncture therapy is more significant.3 Acupuncture and moxibustion treatments both can effectively decrease symptom scores of the patient. It indicates that the two treatments can improve the symptom of dysmenorrheal. It may improve the whole-body situation through analgesia, hence to reduce or eliminate concomitant symptom.4 For treatment of primary dysmenorrhea of congealing cold-damp, acupuncture and moxibustion treatment have no obvious adverse reaction. But only two cases with mild vomiting appeared in the acupuncture group. They can persist in treatment without dealing. It shows that both treatments are safer.5 This study demonstrated that acupuncture and moxibustion therapy has significant analgesic effects and can effectively improve the symptoms of dysmenorrhea. But acupuncture has a faster analgesic onset and a better anxiety state which indicates that acupuncture has goode immediate analgesic effect; moxibustion has no pain and adverse reaction, and the patient feel warm and comfortable which makes to easy to accept. moxibustion has an advantage in this aspect.