Objective: This paper is to observe the clinical curative effect on curing herpes zoster by milli-fire needle therapy and probe into the curative effect and mechanism of action for milli-fire needle therapy in curing damp-retention due to hypofunction of the spleen type herpes zoster with the guiding ideology of “as the yin pathogenic factor,damp evil can noe be expel with out warmth†and “release of fire stagnationâ€.Method: Divide 60 patients meeting the inclusion criterion into two groups: observation group: 30 patients(milli-fire + conventional western medicine group) and control group(general surround needling + conventional western medicine group) through random number table method. Skin lesion part: The milli-fire needle therapy(Burn the conventional 1-inch acupuncture needle to red bright and perform the quick puncture at the operation applying location) is applied to the observation group, and the general surround needling is applied to the control group; Selecting distant points: jiaji acupoints, Zhigou, Houxi, Zusanli, Yinlingquan(mild supplementing and release by normal acupuncture); it shall be cured once a day and one course of curing lasts for 10 days. Each group is cured for one course of curing. Each group is cured with conventional western medicine: taking valaciclovir hydrochloride orally: 500mg/time and twice/day. Taking vitamin B1 orally: 500mg/time and threetimes/day; one course of curing lasts for 10 days and one course of curing is performed in total. In the test process, comprehensive curative effect grading of herpes, herpes stopping time, encrusting time, de-crusting time, pain intensity, degree of pain relief, starting time of pain relief, pain lasting time and immediate analgesic effect shall be observed and recorded; and a follow-up visit shall be paid on the 30 th, 60 th and 90 th day in the test to observe the occurrence of postherpetic neuralgia.Results:Basic information comparison: 60 included cases, 60 cases completed and no de-crusting. There is no statistical significance for the two groups in terms of age, gender, basic signs(body temperature, heart rate, breath and blood pressure), vesication time, VAS grade before curing and comprehensive grading of herpes before curing(P>0.05) and the two groups are not comparable.Herpes Observation:Herpes stopping time: the average time of observation group is 3.79±1.78 days and the one of control group is 5.28±1.86 days; encrusting time: the average time of observation group is 6.38±1.69 days and the one of control group is 8.71±3.01days; de-crusting time: the average time of observation group is 14.97±4.50 days and the one of control group is 18.39±3.53 days; there is statistical significance(P>0.05) for the difference of results above through statistical analysis, and each curative effect index of observation group is superior to the one of control group.Comprehensive curative effect grading of herpes: The grading for theobservation group is 14.78±3.53 before curing and 1.65±1.53 after curing. The grading for the control group is 14.44±2.89 before curing and 4.36±1.89 after curing; there is statistical significance(P<0.05) for the difference of comprehensive curative effect grading of herpes before and after the curing in the group, indicating that the herpes are improved greatly in each group; there is statistical significance(P<0.05) for the difference of comprehensive curative effect grading of herpes before and after the curing between the two groups, indicating the curing effect of observation group is superior to the control group.Pain Observation: Pain intensity(VAS grading): The VAS grading difference for the observation group before and after the curing is 62.66±18.01 and the VAS grading difference for the control group before and after the curing is 54.06±14.97. There is statistical significance(P<0.05) for VAS grading difference before and after the curing in the group, indicating that the pain intensity is ameliorated effectively in each group; there is statistical significance(P<0.05) before and after the curing between the two groups, indicating the pain intensity amelioration effect of the observation group is superior to the one of control group.Degree of pain relief(%): 54.79±3.15 for the observation group and 41.01±3.20 for the control group; starting time of pain relief: 3.50±1.45 days for the observation group and 5.34±2.77 days for control group; pain lasting time: 14.60±13.33 days for the observation group and 25.56±10.68 days for thecontrol group; Immediate analgesic effect: 2.56±0.86 min for observation group and 4.77±1.67 min for the control group; there is statistical significance(P<0.05) for the results in the last 4 observation items through statistical analysis, and the observation group is superior to the control group in each curing effect.There is no statistical significance(P>0.05) for the difference in comparison of PHN occurrence rate and tolerance.To sum up, both the milli-fire needle therapy and the general surround needling therapy have good clinical effect in curing the hypofunction of the spleen type herpes zoster. However, it can be concluded from the comparison results of the observation items above that milli-fire needle therapy is superior to the general surround needling therapy in each curative effect.Conclusion: The milli-fire needle therapy can stop blister faster, expedite the incrustation of skin lesion and fall-off, relieve pain faster and improve the pain obviously, specially having a remarkable effect in immediate analgesic effect and also having certain effect in preventing the postherpetic neuralgia. Thus, it has very high value for clinical application and shall be promoted greatly. |