Eliminate The Wind Cough Soup Type Wind And Pulmonary Infection After Treatment Cough Clinical Observation

ObjectiveIn modern medicine post-infectious cough, (PIC) the pathogenesis, clinical characteristics, the study of the theory of the current Chinese and western medicine therapy, using XiaoBo clinical experience, professor fang "wind cough soup" elimination of dialectical type for wind and pulmonary infection treatment and the therapeutic effect was observed after cough, validation of traditional Chinese medicine in the treatment of infection after cough has a obvious advantage, can bring many after infection in patients with cough more inexpensive and treatment options.MethodsBy including 80 cases included in the standard and do not accord with standard of rule out infection in patients with cough (except lost to follow-up cases), all patients were in March 2014 to October 2015 to zhanjiang second hospital affiliated to guangzhou university of Chinese medicine during outpatient or hospitalization. Put into the group and 80 patients included in the standard according to random number table method randomly divided into research group and the control group in the two groups, one group of 40 people, the control group of 40 people. Two groups of patients than in gender, age, severity, cough, cough symptoms integral visual score and TCM symptoms integral by statistical comparison before treatment, P> 0.05, no statistical difference, study on curative effect difference can be.Team to give an oral (guangdong party pharmaceutical production, grain type of traditional Chinese medicine, Chinese medicine prescription for professor XiaoBo experience basic prescription (wind cough soup), according to the actual clinical dialectic can be appropriate to add and subtract, the medicine cup to add 150-150 ml hot water, then add the traditional Chinese medicine formula particles, stir to dissolve fully warm after oral. Dosage:take 1/ times,2 times/day, at breakfast and dinner after 30 minutes. Control group given routine drug treatment guidelines recommend western medicine, give ketone of fumaric acid for Finn 1 (1.38 mg) 2 times a day, dextromethorphan 15 mg three times a day.Two groups of treatment for 10 days, in the process of the treatment of 4 d,7 d,10 d and 1 week end of the treatment, follow-up and record the observation indexes. Recorded respectively in accordance with the requirements in the corresponding time points corresponding to the two groups of patients treatment time point data:cough, cough symptoms integral visual score and TCM symptoms integral. Each patient prior to the start and end treatment after 1 week of safety monitoring project, in the evaluation of drug safety. All of the patients during treatment observation to ban the use of besides experimental drug drug (external or internal).The clinical data of obtained data using SPSS18.0 statistical software for statistical analysis. Data for the standard deviation of mean soil (), measurement data using t test, counting data with X2 test, hierarchical data with rank and inspection, repeated measurement design using analysis of variance, when P< 0.05 when thinks that there are significant differences between the two groups of data, when P> 0.05 when there was no significant difference between two groups of data. ResultsClinical results analysis showed that (1) using XiaoBo professor away "eliminating wind cough soup" clinical curative effect in treatment group, the degree of symptoms improve relative guidelines recommended by the western medicine control group were more obvious advantages, and less adverse reactions, no obvious side effects. (2), according to the results of clinical research group in the treatment of 40 patients were cured in 17 cases, the cure rate was 42.5% in the observation time window, the total effective rate was 92.5%;And the control group the same treatment of 40 patients,9 cases were cured, the cure rate was 22.5% in the observation time window, the total effective rate was 72.5%. Through statistical analysis of the two groups in curative effect comparison exists significant difference (P< 0.05). Two groups of patients after treatment of cough, cough symptoms integral visual analogue scale, Chinese medicine symptom integral compared with before treatment there is integral has the obvious drop, patients self-conscious symptom improvement, and the two groups after treatment all indexes integral reduced difference through statistical comparison exists significant difference (P< 0.05), shows the team effect is more apparent than in the controls, with statistical significance. (3) in patients after different treatment incidence of adverse reactions are: the two groups after treatment group:7.5%,27.5% in the control group. Team is not found in the process of Chinese medicine in the treatment of liver and kidney function damage and other adverse reactions, and the control group has 11 patients, sleepiness, adverse reactions such as dizziness, or gastrointestinal tract reaction, after drug withdrawal symptoms can disappear. Incidence of adverse events in the two groups to compare the team of the adverse reaction rate is lower than the control group, the X2 test was statistically significant.ConclusionProfessor XiaoBo "eliminating wind cough soup" in the treatment of infection after cough (wind and lung) clinical trials can achieve good clinical effect, and is safe and effective, can effectively relieve the clinical symptoms, is worth popularization in clinical.