The Study Of The Relationship Among TCM Syndrome Types Of CHD Patients, Coronary CTA, Coronary Artery Calcification Score And Blood Lipid

Objective:This study selected out inspection index after the ancient literature search coronary heart disease(CHD) with the progress of modern medicine and previous work. The TCM syndrome types of CHD Patients, the degree of coronary artery lesions shown in Coronary CTA, coronary artery calcification score (CACS) and the lipid levels were collected through retrospective case study to analyze the relationship, thus to provide an objective proof for syndrome differentiation of TCM. At the same time, the correlation between CACS and coronary artery lesions and blood lipid level was also discussed, which provides reference for clinical evaluation of the disease and treatment.Methods:The information of 121 patients who were diagnosed as coronary heart disease using Coronary CTA in Guangdong Province Hospital of TCM in 2015 were collected in this study, which include height, weight, four method of diagnostic information, the result of Coronary CTA, CACS and blood lipid. Then,121 cases of CHD were subjected to TCM syndrome differentiation. Ater that, to create database, and use SPSS 18 statistical software to analyze the correlation between TCM Syndrome Types and the levels of these tests results.Results:1. There were 73 male and 48 female patients, and the number of male is more than female. The number of patients in 50-79 years old is most. The patients’ main Syndrome Types are syndrome of phlegm blocking heart vessel, heart-blood stasis syndrome, syndrome of blood stasis due to qi deficiency, syndrome of qi stagnation and blood stasis and syndrome of deficiency of both qi and yin. The sex and age distribution of each type had no significant difference.2. Syndrome of phlegm blocking heart vessel’s BMI is higher than other groups (P<0.05)3. There were significant differences among different card type by statistically analyzing the results of the degree of coronary artery stenosis、 Lesion count and CACS (P<0.05). Syndrome of qi stagnation and blood stasis and syndrome of deficiency of both qi and yin is more common in patients with single lesion, with moderate stenosis, calcification mainly mild or no calcification. Qi deficiency and blood stasis, blood stasis syndrome is more common in patients with more than two artery lesions, with severe stenosis, moderate to severe calcification. Patients with syndrome of phlegm blocking heart syndrome account for a large proportion of the double vessel disease, severe stenosis group, and the patients widely distributed in various calcium score segments.4. There were significant differences in blood lipid levels among different syndrome types (P<0.05). The cholesterol and low density lipoprotein levels of Qi and yin deficiency syndrome was lower than other syndrome group. The degree of lipid metabolic imbalance of Qi and yin deficiency syndrome was lower than the other. The degree of lipid metabolism imbalance of Phlegm syndrome, blood stasis syndrome is more obvious.5. There is correlation between CACS and age, severity of coronary artery stenosis and number of lesion vessels. The older, the higher the calcification score.Conclusion:Deficiency of Qi, phlegm and blood stasis are the main TCM pathological factors of coronary heart disease. TCM syndrome types were correlated with the degree of coronary artery disease, calcification score and blood lipid level. Coronary CTA, calcification score, blood lipid can be used as the objective index of the syndrome differentiation of coronary heart disease. The calcification score can reflect the extent and range of coronary artery stenosis, and provide basis for clinical diagnosis and treatment.