Correlation Between TCM Classification Of Unstable Angina Pectoris With Coronary Artery Gensini Score And Plasma Atherosclerosis Promoting Index (AIP)

Objective By collecting clinical cases,we observed the correlation between TCM syndrome type of unstable angina pectoris and coronary artery Gensini score,plasma arteriosclerosis promoting index(AIP),analyzed the relationship between relevant indexes and TCM classification of coronary heart disease,and explored the distribution regularity of TCM syndrome type and provide the basis for the objectivity and treatment of TCM syndrome differentiation.MethodIn this study,210 inpatients with positive coronary angiography in the inpatient department of our hospital were selected as the observation group,and 31 healthy persons were selected as the healthy group.The patients were classified by the deputy high-level doctors or above for TCM chest paralysis and heart pain,and the dialectical time was on admission.Record the lipid parameters,calculate the AIP value,calculate the Gensini score according to the condition of coronary artery lesions,and fill in the questionnaire according to relevant information.Results1.The distribution of TCM syndrome type of unstable angina pectoris in coronary heart disease: heart blood stasis syndrome(40.95%)> qi deficiency and blood stasis syndrome(20.95%)> qi and yin deficiency syndrome(19.50%)> qi stagnation and blood stasis syndrome(10.00%)> phlegm barrier syndrome(8.57%).2.The syndrome of heart stasis and stasis by TCM syndrome of unstable angina pectoris was mainly distributed in the severe lesion group of Gensini score,the syndrome of qi deficiency and blood stasis,and the syndrome of phlegm blockage and heart vein were mainly distributed in the moderate lesion group,and the syndrome of qi and yin deficiency was mainly distributed in the mild lesion group.3.There was a certain correlation(P <0.05)between the different types of TCM syndrome and the number of coronary artery lesions in the group of unstable angina pectoris.The clinical differential syndrome of multiple lesions was mainly blood stasis or blood stasis and qi stagnation,while that of patients with turbid phlegm or deficiency of yin was a single lesion.4.The values of AIP in patients with unstable angina pectoris were as follows: heart stasis syndrome(2.23 ± 0.22)> qi stagnation syndrome(2.14 ± 0.19)> qi yin deficiency syndrome(2.07 ± 0.16)> qi deficiency syndrome(2.09 ± 0.17)> phlegm barrier syndrome(2.00 ± 0.13).The Gensini scores of coronary arteries from high to low were as follows: heart stasis syndrome(55 ± 20.75)> qi deficiency syndrome(42.09 ± 20.05)> phlegm obstruction syndrome(38.12 ± 18.92)> qi yin deficiency syndrome(26.96 ± 14.08)> qi stagnation syndrome(26.07 ± 12.57).5.ROC curve indicated that the area under the curve of AIP value in predicting unstable angina of coronary heart disease was 0.735.AIP could be used for predicting unstable angina of coronary heart disease.When AIP value was greater than 2.04,it was more likely to diagnose unstable angina of coronary heart disease.6.The history of hypertension with TCM syndrome in patients with unstable angina pectoris was regular in all groups: the syndrome of heart-blood stasis was different from the syndrome of deficiency of qi and yin,the syndrome of qi deficiency and blood stasis,and the syndrome of phlegm blockage and heart vein(P <0.05).The syndrome of qi stagnation and blood stasis was different from the syndrome of qi deficiency and blood stasis and the syndrome of qi and yin deficiency(P <0.05).7.The AIP value and Gensini score of the syndrome of heart stasis and stagnation were higher than those of other types(P <0.05),and there was a positive correlation between AIP and Gensini score.The TG of the syndrome of blood stasis and stagnation was higher than that of the syndrome of blood blockage and blood stasis(P <0.05),and the HDL-c level of the syndrome of blood stasis and stasis was higher than that of the syndrome of blood stasis and blood stasis(P <0.05).Conclusion 1.The TCM syndrome type of unstable angina pectoris in coronary heart disease is the first syndrome of heart-blood stasis and stagnation,which is divided into the syndrome of qi deficiency and blood stasis,the syndrome of phlegm resistance and heart vein,the syndrome of qi-yin deficiency and qi stagnation and blood stasis and stasis.2.Plasma arteriosclerosis promoting index(AIP)? 2.04 is a risk factor for coronary artery stenosis.It is feasible to use AIP to predict unstable angina pectoris of coronary heart disease.3.There is correlation between TCM syndrome type and AIP and Gensini score in unstable angina pectoris of coronary heart disease,which can provide objective quantitative basis for TCM syndrome differentiation and classification of unstable angina pectoris of coronary heart disease.4.AIP value,Gensini score is the highest,AIP value is the higher,and the clinical differentiation of multiple diseases is the blood stasis or blood stasis and qi stagnation,the most of the patients with turbid sputum or deficiency of yin are single disease,which has great significance.The method of activating blood and removing blood stasis should be paid attention to in clinical treatment.