Correlation Research On Progressive Cerebral Infarction Of Different Syndrome Types In TCM As Well As Their Pathogenic Risks And Prognosis

ObjectivesBased on retrospective analysis of 150 cases with progressive cerebral infarction. We aim to explore the TCM syndrome type distribution characteristics of progressive cerebral infarction, the relationship between syndrome types and ages, pathogenic factors as well a prognosis respectively, so as to improve the early identification, early intervention and achieve better prognosis in patients with progressive cerebral infarction clinically.MethodsThe questionnaires were made for all the patients who met with the diagnostic criteria to record the detailed clinical data. TCM syndrome differentiation was made and NIHSS scores were collected at different stages for the included subjects. Excel 2007 software was applied to establish database of TCM syndrome types, age distribution, risk factors, clinical biochemical examination, NIHSS scores of diverse syndrome types at different ages and stages and the prognosis of different syndrome types with SPSS 13.0 statistical software being used for statistical analysis.ResultsCumulative graphs of both age distribution of different syndrome types and percentage age distribution indicated age differences in the occurrence of progressive cerebral infarction. Significant differences were noticed in both onset and distribution of different syndrome types. Common risk factors of different syndrome types and such biochemical examination indexes as blood lipid, blood coagulation function had statistical differences. Partial statistical differences were detected in NIHSS scores of the same TCM syndrome type at different ages and different periods. The prognosis of different syndrome types were compared to be statistically different.ConclusionAs they get older, there is an increased risk for progressive cerebral infarction. In terms of TCM syndrome type distribution, the order from high to low incidence should be blood stasis in collectrals type, phlegm-stasis in channels type, hyperactivity of liver-yang type, wind phlegm obstruction in collectrals type, wind formation from yin deficiency type and qi deficiency and blood stasis type. Phlegm-stasis in channels type and blood stasis in collectrals type are closely associated with carotid plaques, while hyperactivity of liver-yang type and wind formation from yin deficiency type are closely related to high blood pressure and diabetes. There are significant differences among different syndrome types in LDL and PT, More evident differences can be noticed in the comparison of PT and APTT in the type of blood stasis. NIHSS scores experience significant differences before and after treatment in the types of both phlegm-stasis and blood stasis. Patients of phlegm-stasis in channels type and qi deficiency and blood stasis type have poorer prognosises, whereas those of blood-stasis in collectrals type and hyperactivity of liver-yang type enjoy a better prognosis.