Analysis Of Risk Factors And Coronary Characteristics Of Coronary Heart Disease In Women Before And After Menopause

Objective:To compare the clinical features and coronary characteristics of coronary heart disease in women before and after menopause.Methods:Retrospectively analyzed the clinical data of female patients diagnosed with coronary heart disease during December 2016,January 2017.According to the menopause condition,the clinical data were divided into preand postmenopausal groups.According to the collected clinical data,the risk factors and coronary angiography characteristics were analyzed by SPSS software.Results:There were 223 patients in total,including 48 cases without menopause.There were 175 cases in menopausal group.Analysis of risk factors: the family history of coronary heart disease and serum cholesterol level in premenopausal women with coronary heart disease were significantly higher than those in postmenopausal women(P < 0.05).The risk factors such as hypertension history,diabetes history,serum triglyceride,low density lipoprotein cholesterol,high uric acid,white blood cell count and fibrinogen were higher in postmenopausal women with coronary heart disease(P < 0.05).There were statistical differences.Female smoking history,high density lipoprotein cholesterol level in premenopausal women with coronary heart disease,blood glucose level in premenopausal women with coronary heart disease is low,P > 0.05,do not have Statistical differences.Location analysis of coronary heart disease: The proportion of left main lesions in premenopausal women with coronary heart disease was higher than that in postmenopausal women with coronary heart disease,P was greater than 0.05,with statistical difference.The proportion of anterior descending and circumflex lesions in premenopausal women with coronary heart disease was lower than that in postmenopausal women with coronary heart disease,P was greater than 0.05,and there was no statistical difference.The proportion of right coronary artery disease in premenopausal women with coronary heart disease is lower than that in postmenopausal women with coronary heart disease,P is less than 0.05,with statistical difference.In women with coronary heart disease,the anterior descending artery is the most common,and the pre-menopausal women with coronary heart disease are less affected by the right and left circumflex.Analysis of the characteristics of coronary artery disease: compared with postmenopausal women with coronary heart disease,single vessel disease was more common in premenopausal women with coronary heart disease,mainly single vessel disease,P < 0.05,which was statistically significant.The incidence of multi-vessel disease was higher in postmenopausal women with coronary heart disease(P < 0.05),which was statistically significant.Coronary artery disease score analysis: compared with pre-menopausal women,Group 1 accounted for a higher proportion of coronary heart disease in premenopausal women(P < 0.05),and group 2 accounted for a higher proportion of coronary heart disease in premenopausal women(P > 0.05),which was not statistically significant.Group 3 accounted for a higher proportion of postmenopausal women with coronary heart disease(P > 0.05),and group 4 and group 5 accounted for a higher proportion of postmenopausal women with coronary heart disease(P < 0.05),which was statistically significant.Single factor logistic regression analysis of coronary heart disease in premenopausal women: taking postmenopausal women with coronary heart disease as control group,the risk factors of premenopausal women with coronary heart disease were analyzed by single factor.Logistic regression analysis showed that hypertension history,family history of coronary heart disease,fibrinogen and serum cholesterol were the risk factors of premenopausal women with coronary heart disease(P < 0.05).Age is a protective factor in premenopausal women with coronary heart disease(P < 0.05).Multivariate logistic regression analysis of coronary heart disease in premenopausal women: taking postmenopausal women with coronary heart disease as control group,univariate logistic regression analysis was performed on the risk factors of premenopausal women with coronary heart disease.Results the meaningful indexes were analyzed by multivariate logistic regression analysis,and the results showed that fiber eggs White original,serum cholesterol are the risk factors of premenopausal women with coronary heart disease,P is less than 0.05;age is the protective factor of pre-menopausal women with coronary heart disease,P is less than 0.05.Conclusion:1.The common risk factors for coronary heart disease are hypertension,hyperlipidemia,diabetes,family history of coronary heart disease,and smoking.The pre-menopausal and post-menopausal women were compared with the post-menopausal group according to these risk factors,and it was found that the family history of hypertension,diabetes and coronary heart disease was of statistical significance and that smoking did not have statistical difference;compared with the biochemical indexes of the pre-and post-menopausal women with coronary heart disease,high-density lipoprotein cholesterol in premenopausal group(The level of HDL-C was high and the blood sugar level was low.The difference between the two groups was not statistically significant.The serum total cholesterol(TC)level in the premenopausal group was high,and the difference between the two groups was of statistical significance.The white blood cell count,serum triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C)in the post-menopausal group were significant.The levels of serum uric acid,fibrinogen and white blood cell count were high,and the difference between the two groups was statistically significant.The pre-menopausal women with coronary heart disease(CHD)were mainly single-branch,and the double-branch and multiple-branch lesions were found in the postmenopausal women with coronary heart disease.The most frequently accumulated and pre-menopausal women with coronary heart disease in the patients with coronary heart disease The right crown and left circumflex branch were less involved.4.The degree of coronary artery disease in premenopausal women with coronary heart disease was low,and the Gensini score was low.The degree of coronary artery disease in postmenopausal women with coronary heart disease was serious,and the Gensini score was high.5.Taking postmenopausal women with coronary heart disease as control group,logsitic analysis of risk factors of coronary heart disease in premenopausal women showed that fibrinogen and serum cholesterol were the main risk factors of premenopausal women,and age had protective effect on premenopausal women.