Clinical Observation Of Gengnian Shushi Soup In Treating Perimenopausal Syndrome

Objective Objectively evaluate the clinical efficacy of Gengnian Shushi Soup for perimenopausal syndrome(the kidney-yin-yang deficiency type),as well as its treatment mechanism and safety analysis.Methods In this study,from January 2019 to December 2019,among 74 patients with Perimenopausal Syndrome who were treated in the outpatient department and ward of the Chinese Medicine Department of the People's Hospital of Inner Mongolia Autonomous Region,this study will be selecte 74 patients in strict accordance with the criteria for case inclusion(TCM syndrome differentiation is kidney-yin and yang deficiency type).Virtual type.The random number table method was used to divide into the Linguan group and the control group,with 37 cases in each group.The Gengnian Shushi Soup group was used in the Linguan group and the Jiarong tablet was used in the control group.Dosing was continued for 4 weeks.After the administration,changes in the main indexes such as kupperman score,TCM syndrome score,and serum hormones(E2,FSH,LH)were observed before and after the two groups,and the efficacy was evaluated.Results 1.Comprehensive effect comparison: The total effective rate of Linguan group was 94.4% higher than that of control group 72.2%(P<0.05);2.Comparison of improved kupperman scores: After treatment,the kupperman scores of Linguan group and control group were both higher than before The reduction(P<0.05),compared between the two groups after treatment,the Linguan group decreased more significantly than the control group(P<0.05);3.Comparison of TCM symptom score points: the total score of the Linguan group and the control group after treatment All of them have decreased before(P<0.05),and the decrease in Linguan group is more obvious than that in the control group(P<0.05);4.Comparison of the efficacy of single symptoms of traditional Chinese medicine: Linguan group improves heat sweating,waist and knee weakness,burnout The effects of fatigue,dizziness,tinnitus,and irritability were better than those in the control group(P<0.05);5 Comparison of serum hormone levels: E2 in the Linguan group and the control group increased after treatment(P<0.05),FSH and LH were lower than before(P<0.05).Comparison between the two groups after treatment showed that the Linguan group was better than the control group in the increase of E2 and the reduction of FSH and LH(P<0.05).Conclusion 1.Gengnian Comfort Soup has a good effect of nourishing kidney essence,clearing away fire,warming kidney yang and regulating Chong Ren;2.Gengnian Comfort Soup can obviously reduce various clinical symptoms of Perimenopausal Syndrome,such as hot flashes,sweating,anxiety,insomnia,etc 3.Gengnian Comfort Soup can improve serum sex hormone levels;4.Gengnian Comfort Soup has good security,no other adverse reactions such as allergies,it has the value of in-depth clinical research and promotion.