| Objective:The aim is to explore the effects of warm acupuncture on bone marrow suppression and quality of life in deficiency of qi and blood type patients with non-small cell lung cancer(NSCLC)with qi and blood deficiency before and after chemotherapy,so as to provide a reliable basis for clinical studiesMethod:Using a randomized controlled study,68 patients with non-small cell lung cancer(NSCLC)with qi and blood deficiency after palliative chemotherapy were randomly divided into moxibustion group(n=34)and traditional Chinese medicine group(n=34).Two groups of patients began to take elm white tablets the day before chemotherapy(two pills three times a day,orally).In the moxibustion group,zusanli(shuang),sanyinjiao(shuang),xuehai(shuang),and guan yuan points were treated with warm acupuncture.Each point had 2 strong ai zhu,and the burning time of each strong ai zhu was about 10min,20min each time.The TCM group was treated with ulmus ulmus raw white tablets(two pills each time,three times a day)for a total of 10 times.Before chemotherapy,chemotherapy(day 1),(10 days)treatment,after treatment and follow-up(1 month after treatment)for routine blood(white blood cells,neutrophils,lymphocytes,platelet,hemoglobin,red blood cells),Interleukin-6(Interleukin-6,IL-6)detection and determination of cancer patients quality of life scale(EORTC QLQ C30)score of acquisition.Results:1.Blood routine and interleukin-il-6:(1)intra-group comparison:after treatment,WBC,neutrophilic granulocyte,platelet,hemoglobin and erythrocyte increased significantly compared with that after chemotherapy,and the difference was statistically significant(P<0.05).There was no significant difference between lymphocytes and il-6(P>0.05).Control group:after treatment,only white blood cells were significantly increased compared with that after chemotherapy,and the difference was statistically significant(P<0.05),while there were no significant differences in neutrophils,lymphocytes,platelets,hemoglobin and red blood cells(P<0.05)(2)comparison between groups:after treatment,compared with that after chemotherapy,the number of WBC in the wenzhen group increased significantly,which was significantly different from that in the control group(P<0.05).Before and after chemotherapy,the amount of hemoglobin in the wenzhen group was higher than that in the control group,and the difference was statistically significant(P<0.05)2.The EORTC Quality of Life Questionnaire-Core 30,EORTC QLQ-C30(1)intra-group comparison:body function,emotional function,emotional function,overall health status,fatigue,nausea and vomiting,pain,shortness of breath,loss of appetite,constipation and overall quality of life were significantly reduced in the wenneedling group after treatment compared with that after chemotherapy,and the difference was statistically significant(P<0.05).In the control group,the total health status and pain scores were significantly reduced,and the difference was statistically significant(P<0.05).After 1 month of follow-up and treatment,the body function,emotional function,overall health status,fatigue,nausea and vomiting,shortness of breath,pain,loss of appetite,and overall quality of life score of the warm acupuncture group all decreased,and the difference was statistically significant.Control group:total health status,pain,shortness of breath,loss of appetite,and overall quality of life score were all decreased,and the difference was statistically significant(2)comparison between groups:the scores of body function,emotional function,total health status,fatigue,nausea and vomiting,pain,shortness of breath,loss of appetite,constipation and overall quality of life in the wenneedling group were significantly lower than those in the control group after treatment compared with after chemotherapy,and the differences were statistically significant(P<0.05).After 1 month follow-up,the scores of body function,emotional function,general health,nausea and vomiting,shortness of breath,and overall quality of life in the wenzhan group were significantly lower than those in the control group(P<0.05)Conclusion:1.Moxibustion combined with moxibustion can significantly improve the bone marrow suppression in patients with non-small cell lung cancer with qi-blood deficiency after chemotherapy,and effectively regulate and promote the immune function of the body2.Moxibustion combined with medicine can significantly improve the quality of life of patients with non-small cell lung cancer with qi-blood deficiency after chemotherapy3.Moxibustion combined with moxibustion can produce a synergistic effect on bone marrow suppression and improvement of life quality in patients with non-small cell lung cancer with qi-blood deficiency after chemotherapy. |
PDF Full Text Request