| OBJECTIVE:Data mining technology is used to explore the characteristics of the syndrome distribution and the clinical medication law in the medical cases of Xulao(severe disease procrastinate period)METHODS:The past medical history of a patient admitted to the intensive care unit of a hospital between January 2015 and December 2019 with a diagnosis consistent with "Xulao(severe disease procrastinate period)" was selected by combining the diagnostic,inclusion and exclusion criteria.A total of 48 eligible patients,98 hospitalizations and 196 medication prescriptions were obtained.Microsoft Office Access software was used to set up a database on wasted work(extended stay for severe cases).The data entry was performed by classifying the patients’ symptoms,TCM symptoms,composition of TCM and sexual flavors,and finally the data were processed and analyzed by SPSS 19.0 and SPSS MODELER software were used to process and analyze the data.RESULTS:1 Chinese medicine symptoms:the ratio of men to women is about 2:1,and the age of patients is mostly between 80-89 years old.The most common causes of disease are prolonged illness,external aggression and fatigue.The common clinical symptoms are emaciation,fatigue,facial pallor,coughing and spitting,and lassitude,Lack of energy,low voice,lazy speech,irritability,dullness,bad food,spontaneous sweating.Tongue like more concentrated in the tongue with cracks,pale tongue,pale fat tongue,dull red tongue,tongue edge medium tooth marks.Tongue is mainly flake/less mossy,slightly greasy,thin white.Pulse is fine>weak>sunken>stringen>smooth>jerky>moist>numerical trend distribution;Symptom clustering analysis yielded six cluster combinations.The distribution trend of pathological elements is Qi deficiency>Yindeficiency>Yang deficiency>Bloodde ficiency>Phlegm-dampness>Blood stasis>Heatiness>Stagnation.The distribution trend of pathological elements is Lung>Spleen>Kidney>Heart>Liver.The combination of pathogenic elements is dominated by qi deficiency+lung and spleen and qi deficiency and yin deficiency+lung and spleen There are a total of five types of Chinese medicine certificates:Lung-Spleen-Qi deficiency,Lung-Spleen-Qi-Yin deficiency,Spleen-Kidney deficiency,Heart-Lung-Qi-Blood deficiency and Lung-Qi deficiency with Phlegm-Dampness internal stagnation2 The regular part of traditional Chinese medicine:Among the 196 prescription medicines,the distribution trend of traditional Chinese medicine types is in the following direction:Tonifying medicine>Diuretic wetting medicine>antipyretic medicine>calm the mind medicine>regulate the qi flow medicine>digestive aid medicine>invigorate blood circulation and remove blood stasis medicine>Wenli medicine>Huashi medicine>astringent medicine 143 Chinese herbal medicines were used in total and 37 herbal medicines were used more than 20 times.The trend of the distribution of Chinese medicinal properties is warm>flat>slightly warm>cold>slightly cold>hot.Taste distribution trend of Chinese herbal medicine is sweet and bland>bitter>pungent>sour>salty.The trend of distribution of Chinese herbal medicine to the Lung>Spleen>Kidney>Heart>Liver.A total of 22 relationships were obtained from the Chinese medicine association rule(support 70,confidence level 0.8).CONCLUSION:Data mining of past clinical cases shows that the prevalence of Xulao(severe disease procrastinate period)is more common in the elderly.clinical symptoms are common in the Weight loss,mental fatigue,and facial pallor.TCM common symptoms include deficiency of qi and yin and yang in the lungs,spleen,and kidneys.There are mainly types of Chinese medicine certificates:Lung-Spleen-Qi deficiency,Lung-Spleen-Qi-Yin deficiency,Spleen-Kidney deficiency,Heart-Lung-Qi-Blood deficiency and Lung-Qi deficiency with Phlegm-Dampness internal stagnation.Treatment,clinical mainly to replenish the deficiency medicine mainly,sweet and bland and belongs to the spleen,kidney class Chinese medicine is particularly beneficial,in the formula dispatch medicine,often to astragalus with fried Atractylodis Macrocephalae strengthens Qi,invigorates the spleen and stomach,while Astragalus and Poria are combined to invigorate the spleen,invigorate Qi,induce diuresis and reduce swelling With the same complementary yin and yang and table and lung energy,astragalus with yam benefits the lungs and nourishes lung yin,warms the spleen and yang and nourishes stomach yin,solidifies kidney essence and warms kidney water.Xulao(severe disease procrastinate period)are concentrated in the five organs,mainly due to deficiency of qi and blood,yin and yang,so clinical diagnosis and treatment should focus on the five organs,and the treatment will follow the "deficiency is to make up for it".The principle of "the loser benefits".When replenishing a deficiency,one should adopt the treatment method of benefiting qi,warming yang,nourishing blood and nourishing yin according to the nature of the disease;the other should combine the five organs.The location of the disease is biased and treated with a more targeted prescription.In addition,as the duration of the disease is relatively long,we should pay attention to whether there is any deficiency in the middle of the real situation,and adopt the methods of tonifying rather than diarrhea,strengthening the positive and eliminating the evil.The treatment concept to achieve the goal of treating both the symptoms and the disease. |