Investigation On Centrifugal Spinning Equipment And Process Of Functional Fiber Membrane

The micro-nano structure has huge application potential due to its excellent performance.As one of many micro-nano structures,micro-nano fibers can be manufactured through a variety of processes.Among them,centrifugal spinning has attracted more and more researchers' attention due to its outstanding advantages such as large output and low energy consumption.Centrifugal spinning is a new process for manufacturing micro-nano fibers.Its working principle is to use centrifugal force to throw liquid polymer out of stretching and refine to form fibers.This paper focuses on the exploration of centrifugal spinning technology,including the research and development of the device,the exploration of process parameters,the preliminary exploration of the application,and the improvement and verification of the device.The first work carried out was to design and construct a centrifugal spinning device.First,the fiber forming mechanism of centrifugal spinning is briefly analyzed,then the model of the device is established,and finally the parts are purchased and assembled.After the centrifugal spinning device was assembled,the device was debugged and used to manufacture micro-nano fibers.The test results showed that the device was stable in function and met the design requirements.Then through orthogonal experiment to explore the influence of process parameters on fiber forming quality.A self-made centrifugal spinning device is used to manufacture PVP/PEO composite fiber membrane.The average fiber diameter and its coefficient of variation are used as the basis for evaluation.The spinneret speed,solution concentration,spinneret hole diameter and ambient temperature are explored through orthogonal experiments.The influence of four important parameters on the quality of fiber forming,and thus get the appropriate process parameters.Finally,a verification experiment of process parameters was carried out,and the results showed that this set of parameters can be used to prepare fiber membranes with a smaller average diameter and better fiber uniformity.Then,in order to expand the application of centrifugal spinning,the centrifugal spinning device was improved,and the optimization design was assisted by simulation,and the effect of the optimization design was verified through experiments.Specifically,needle and needleless spinnerets are designed and COMSOL is used to simulate the flow field and electric field.The simulation results show that the needle-free spinneret is a better design.A collection device using different types of electrodes is designed and the simulation results show that the ring-shaped cylindrical electrode has a better concentration effect on the electric field,and the ring-shaped chip electrode has a higher electric field intensity.The improved device was used to prepare oriented fibers to verify the improvement effect.The orientation analysis of the fibers obtained in the experiment found that the improved device can be used to prepare oriented fibers.The fiber orientation is better by using needleless spinneret and ring-shaped chip electrode.Through tensile experiments,it is found that oriented fibers have better uniaxial mechanical properties than ordinary fibers.Finally,a preliminary study on the application of centrifugal spinning was carried out,and a fast-dissolving drug-loaded fiber film was fabricated.Paracetamol(APAP)was selected as the target drug and added to the PVP/PEO mixed solution,and the instant drug-loaded fiber film was fabricated by using the process parameters obtained by the orthogonal experiment.By using SEM,FTIR,XRD and DSC,it was found that APAP could be well compatible with PVP/PEO in amorphous form,which indicated that the drug-loaded fiber film contained the target drug.The rapid dissolution performance of the drug-loaded fiber film was characterized by the fast dissolution experiment,and it can be found that the drug-loaded fiber film sample can basically be dissolved within 9 s.