| Objective To investigate the correlation between cold and heat syndromes and physical and chemical indexes as well as depression and anxiety scores in elderly patients with coronary heart disease.It provides objective basis for TCM syndrome differentiation and diagnosis of CHD in the elderly.Methods A total of 162 elderly patients with coronary heart disease who were admitted to the cadre health department of Qingdao hospital of traditional Chinese medicine(Qingdao Hai Ci Medical Group)from September 2017 to January2020 and met the diagnosis of fever and cold were selected.The heat syndrome group includes phlegm heat syndrome(Heat of turbid phlegm)and heart kidney Yin deficiency syndrome.Cold syndrome group includes cold coagulation heart pulse syndrome and heart and kidney Yang deficiency syndrome.Collect basic information and auxiliary examination related to admission.Gender,age,heart rate,blood pressure,co-morbidity,depression score,anxiety score,heart function and other indicators of the two groups were statistically studied by SPSS25.Logistic multiple regression was used to analyze the correlation between CHD and physical and chemical indexes.Screening the related factors of CHD.Gender,age,heart rate,blood pressure,co-morbidity,depression score,anxiety score,heart function and other indicators of the two groups were statistically studied by SPSS25.Logistic multiple regression was used to analyze the correlation between CHD and physical and chemical indexes.Screening the related factors of CHD.Results 1.There was a significant difference in heart rate distribution between the two groups of elderly CHD,P=0.043 < 0.05,and the heat syndrome group was higher than the cold syndrome group.2.There was a significant difference in the distribution of hs-crp in the elderly CHD group and CHD group(P=0.012 < 0.05),and hs-crp in the heat syndrome group was higher than that in the cold syndrome group.Results 1.There was a significant difference in heart rate distribution between the two groups of elderly CHD,P=0.043 < 0.05,and the heat syndrome group was higher than the cold syndrome group.2.There was a significant difference in the distribution of hs-crp in the elderly CHD group and CHD group(P=0.012 < 0.05),and hs-crp in the heat syndrome group was higher than that in the cold syndrome group.3.There were significant differences in TG,TC,hdl-c and ldl-c distribution in the CHD cold and heat syndrome group,with P values of 0.009,0.001,0.033 and 0.041,respectively,all < 0.05,and TG,TC and ldl-c in the heat syndrome group were higher than that in the cold syndrome group,while hdl-c heat syndrome group was lower than that in the cold syndrome group.4.There was a significant difference in blood glucose distribution in the elderly CHD cold and heat syndrome group(P=0.037 < 0.05),and fasting blood glucose in the heat syndrome group was higher than that in the cold syndrome group.5.There was a significant difference in uric acid distribution between the two groups,P=0.035 < 0.05,and the heat syndrome group was higher than the cold syndrome group,which had statistical significance.6.The ejection fraction of the cold syndrome group was lower than that of the heat syndrome group,with a significant difference(P=0.000).7.There was a significant difference in FIB distribution between the two groups(P=0.008 < 0.05),and the heat syndrome group was higher than the cold syndrome group,which was statistically significant.8.There was a significant difference in BNP distribution between the two groups(P=0.049 < 0.05),and BNP in the heat syndrome group was lower than that in the cold syndrome group,with statistical significance.9.There was a significant difference in the distribution of anxiety/depression scores between the two groups,with P values of 0.001 and 0.010,respectively,both< 0.05,and the anxiety score in the heat syndrome group was higher than that in the cold syndrome group,while the depression score in the cold syndrome group was higher than that in the heat syndrome group,with statistical significance.10.Elderly patients with coronary heart disease accompanied by anxiety mainly focus on heat syndrome,while patients with depression are more common in cold syndrome.11.Heat syndrome of coronary heart disease in the elderly is closely related to hs-crp and FIB;The cold syndrome of coronary heart disease in the elderly is closely related to BNP and EF.Conclusion 1.There were significant differences in the distribution of heart rate,blood lipid,blood glucose,BNP,FIB,hs-crp,uric acid,heart function and anxiety score/depression score between the cold and heat syndrome types of elderly patients with coronary heart disease.2.Among the elderly patients with coronary heart disease in Qingdao hospital of traditional Chinese medicine,the TCM syndromes complicated with anxiety were mainly heat syndromes,while the TCM syndromes complicated with depression were mainly cold syndromes.3.FIB,hs-crp,EF and BNP are correlated with the syndromes of coronary heart disease in the elderly.Low BNP and low EF may be used as the basis of syndrome differentiation and diagnosis of CHD. |
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