| Objective: To observe the clinical efficacy and safety of Haitang Shufeng Decoction combined with calcipotriol liniment in the treatment of blood-heat syndrome of scalp psoriasis vulgaris.Methods:This study was a randomized controlled trial,with a total of 99 cases included.According to the random number table method,the patients were randomly divided into 3 groups,including the experimental group,control group 1 and control group2,with 33 cases in each group.The experimental group was given Haitang Shufeng Decoction combined with Calcipotriol Liniment.Control group 1 took Haitang Shufeng Decoction orally.Control group 2 was treated with Calcipotriol Liniment,and the treatment course of the three groups was 4 weeks.The PSSI scores,TCM syndrome scores,adverse reactions and recurrence were observed and compared between the three groups before and after treatment.SPSS24.0 software was used for statistical analysis of the data,and the results were obtained and discussed.Results:1.Among the 1.99 patients,a total of 6 cases fell off,and the final effective cases were93 cases.Before treatment,the differences in gender,age,course of disease,PSSI score,and TCM syndrome score between the three groups of patients were not statistically significant(P>0.05),and they were comparable.2.Comparing the efficacy of the three groups after treatment,the total effectiverate of the experimental group is 96.77%,which is higher than 83.87% of the cont rol group 1 and 74.19% of the control group 2;the difference between the experim ental group and the control group 1 is statistically significant(P<0.05);The differen ce between the experimental group and the control group 2 is statistically significan t(P<0.05).3.After treatment,the PSSI scores of the three groups were lower than before treatment,and the differences within the groups were statistically significant(P<0.05);comparison between the groups,the PSSI score reduction of the experimental group was significantly better than that of the control group 1 and the control group 2,the difference is statistically significant(P<0.05).4.After treatment,the scores of TCM syndromes in the three groups were lower than before treatment.In comparison between the groups,the difference between the experimental group and the control group 1 before and after treatment was statistically significant(P<0.05),and the difference between the control group 2 and before and after treatment was not statistically significant.Significance(P>0.05);in comparison between groups,the difference between the test group and the control group 1 was not statistically significant(P>0.05),and the difference between the test group and the control group 2 was statistically significant(P<0.05).After treatment in group 5.3,the detection rate of Pityrosporum was reduced,but there was no statistically significant difference in comparison within and between groups(P>0.05).6.The number of adverse reactions in the experimental group was 2;the number of adverse reactions in the control group 1 was 1;the number of adverse reactions in the control group 2 was 4 cases.7.After the course of treatment was followed up for 3 months,the recurrence rates of the test group,the control group 1,and the control group 2 were 8.70%,31.25%,and50.00%,respectively.Comparing the experimental group with the control group 1 and the control group 2,the difference was statistically significant(P<0.05).Conclusion:1.Haitang Shufeng Decoction combined with Calcipotriol Liniment has a reliable efficacy in the treatment of blood heat syndrome of scalp psoriasis vulgaris,which is better than oral Chinese medicine alone and Calcipotriol Liniment alone.2.Haitang Shufeng Decoction combined with Calcipotriol Liniment in the treatment of blood heat syndrome of scalp psoriasis vulgaris has a lower recurrence rate,less adverse reactions and high safety compared with oral traditional Chinese medicine and Calcipotriol Liniment alone,which is worthy of clinical promotion and use. |
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