Based On The Traditional Chinese Medicine Inheritance Auxiliary Platform To Explore Professor Yuan Huishu’s Medication Rules In The Treatment Of Essential Hypertension

Objective:To explore the prescription rules and clinical experience of Professor Yuan Huishu in the treatment of essential hypertension,and to provide ideas and methods for the standardization of traditional Chinese medicine in the treatment of essential h ypertension through the retrospective study of Professor Yuan Huishu’s outpatient treat ment of essential hypertension.Methods:The initial medical records of patients diagnosed as essential hypertension in the outpatient department of the Second Affiliated Hospital of Heilongjiang Universit y of Chinese Medicine were collected from Professor Yuan Huishu’s during October2016 to March 2019.The relevant medical case data were sorted out,and the medic al case data that met the inclusion criteria were input into the clinical information co llection system of the "TCM Inheritance Assist Platform".Using the functions of "Sta tistical Report" and "System Analysis" in the application system,clinical study data were obtained.Results:1.Basic information of patients: a total of 581 medical cases were eligible for i nclusion,including 334 female patients,accounting for 57% of the total number;A t otal of 247 male patients accounted for 43% of the total number.2.Drug-induced taste return(1)Four Qi statistics: the supervisor used warm drugs for 3,501 times,accountin g for 31.93% of the total;3495 times,accounting for 31.87% of the total;Cold drug s were used 3178 times,accounting for 28.98% of the total;Cold drugs were used 752 times,accounting for 6.86% of the total;Thermogenic drugs were used 40 times,accounting for 0.36% of the total.(2)Five flavors statistics: 6286 times of the instructor’s use of sweet drugs,acco unting for 35.39% of the total;Bitter taste was used 4912 times,accounting for 27.66% of the total.3658 times,accounting for 20.60% of the total;Sour taste was used1151 times,accounting for 6.48% of the total;Saltiness was used 1006 times,accou nting for 5.66% of the total;The astringency was used 748 times,accounting for 4.21% of the total.(3)The statistics of meridian returning: the top 6 meridians returning by drugs used by the tutor were liver,kidney,spleen,heart,lung and stomach,with frequencies of 6277,3786,3764,3566,3212 and 2647 times respectively;Accounted for 22.56%,13.61%,13.53%,12.82%,11.55%,9.52% of the total frequency of use,respectiv ely.3.Frequency of drug use: Among the 581 prescriptions,198 kinds of traditional Chinese medicine were used by the tutor,with a total of 11,094 times,among whic h the top 40 traditional Chinese medicines were used 8,719 times,accounting for 78.59% of the total times.According to the frequency of use,the 40 traditional Chinese medicines were shown as follows: Poria cocos,gastrodia elata,uncaria,oysters,keel,dried tangerine or orange peel,atractylodes,polygala,radix bupleuri,zizyphus jujube kernel,achyranthes,chicken’s gizzard-membrane,notoginseng,rhizoma ligustici wallic hii,yam,dogwood,haliotis,cortex moutan,radix rehmanniae,chrysanthemum,cortex albiziae,astragalus,cassia seed,radix glycyrrhizae,radix curcumae,alisma,scorpion,radix scutellariae,cortex phellodendri,ginseng,angelica sinensis,rhizoma anemarrhena e,rhizoma atractylodis,divine comedy,pinellia,radish seed,salvia miltiorrhiza,Areca nut,white peony root,mother of pearl.4.Rules of drug formulation(1)The supervisor’s common drug group includes: Keel-oysters,gastrodia elata,uncaria,atractylodes,poria cocos,poria cocos-keel-oysters-polygala,dried tangerine or orange peel,radix bupleuri,keel-oysters-gastrodia elata,uncaria,zizyphus jujube kernel,polygala,dried tangerine or orange peel-atractylodes poria cocos,atr actylodes poria cocos-uncaria gastrodia elata,chicken’s gizzard-membrane,atractylod es,poria cocos,twotooth achyranthes root-haliotis-teng-gastrodia elata,yam-c ornel-radix rehmanniae,13 groups,such as Chuanxiong,Unkunteng and Gastrodia elata,etc.(2)The core medicines of the teacher for the treatment of hypertension include:gastrodia elata,uncarpus teng,keel,oyster,ox knee,chicken root,tangerine peel,pol ygon,bupleurum,jujube seed,atractylodes,poria cocos,notoginseng,chuanxiong,raw land,yam,dogwood,chrysanthemum,cassia,peony bark,Albizia bark and other 21traditional Chinese medicines.5.New combination: G1.Codonopsis codonopsis,Radix Sophora,Radix Aconitu m,Ochre,Citrus aurantii,Magnolia officinalis.G2.Chuan Melia Seed,Yu Li Ren,Rhubarb,Buddha’s Hand.G3.Zalanthus,Polygala,Niejiaoteng,Cassiae Seed,Knotweed,Hawthorn.G4.Coix Seed,Rehmannia glutinosa,Anemarrhenia,Alisma Alisma,Cork Peony,Phellodendron chinense.Conclusion:1.The supervisor usually uses cold,calm and warm drugs in the treatment of hypertension;Its medicinal taste is sweet,bitter,pungent three flavors;Its return to the liver,kidney,spleen three meridians.2.The instructor believes that the treatment of hypertension should be based on t he syndrome differentiation of liver,kidney and spleen.The treatment principle is toreplenish deficiency and reduce compactness,and adjust Yin and Yang.The treatment of deficiency syndrome should nourish the liver and kidney,replenish qi and nourish blood;Treatment evidence should be liver Qianyang,liver purging fire,liver qi,Fu Fu diarrhea heat,clearing damp phlegm,blood circulation silt.3.When treating hypertension,the tutor attaches importance to the mental and mental recuperation and the care of the spleen and stomach.