Analysis Of Risk Factors And Syndrome Elements In High-risk Stroke Population With Hypertension

ObjectsTo investigate the risk factors and syndrome factors of people at high risk of stroke with hypertension,so as to provide objective evidence for syndrome differentiation and treatment.Methods1 By cross-sectional survey method,community resident population over 40,in Lugouqiao,Xinglong,Dahongmen and Tieying which belonged to Fengtai District of Beijing,were investigated,from December 2013 to February 2015.750 patients of hypertension diagnosed and combined variety of stroke risk factors(Hypertension group)were included,also 535 patients without hypertension and combined variety of stroke risk factors(Non-hypertension group).The demographic information,stroke risk factors,medicine using,carotid ultrasound reports and traditional chinese medical four diagnostic information were documented.2 A data management plantform was established based on Epidata 3.1,data established by double input and double check independentedly.Statistics were processed by SPSS 21.0.The common factors were extracted by factor analysis,and the syndrome factors were setted via multilateral negotiations;To analyze the risk factors related to sieve out the strong association rules using the algorithm of association rules Apriori of C lementine 12.0.Results1 The general information distributionThe demographic information,age,gender,educational level,individual average medical expenditure differences was statistically significant within Hypertension group and Non-hypertension group;male,older age,lower level of education were risks for high blood pressure.Bad living and diet habits like lack of exercise and salty taste was widespread;Salty taste difference was statistically significant.2 The risk factors analysisAbout risk factors distribution,age,gender,stroke and TIA history,diabetes history,obesity was statistically significant between two groups,meanwhile with higher obesity rate.About drug treatment of disease performance,oral glucose-lowering,lipid-lowering and antiplate let medication rate significantly higher than that of the hypertension group,but wrose in quit smoking and sports impro vement.About the risk factors for correlation,in the study population,the strong association of risk factors mainly performance for high blood pressure and obesity,age,gender,hyperlipidemia;hypertension and stroke,age,gender;hyperlipidemia and obesity,diabetes,coronary heart disease,etc.Hypertension group mainly for hyperlipidemia and obesity,diabetes;hyperlipidemia and coronary heart disease,age;gender,hyperlipidemia and hypertension duration,etc.And Non-hypertension group mainly for hyperlipidemia and diabetes,TIA;hyperlipidemia and obesity,etc.Through analysis found that high blood pressure with men>65 years old and women>55 years old,were the high risk factors of stroke.Hyperlipidemia,obesity,diabetes in people at high risk of stroke with hypertension were common,and associated with higher hypertension duration,especially in hyperlipidemia.As the some time,carotid atherosclerotic lesions significantly in Hypertension group with higher incidence of plaque,more irregular,low and mixed echo and higher carotid stenosis rate,the difference between groups was statistically significant.3 Blood pressure levels and the relevant influence factors analysisThe blood pressure level classification was positively associated with stroke risk,also hyperlipidemia,obesity and diabetes.The population getting a good medication compliance;blood pressure target group and non-target group converged in drug selection and combination,medicine using had a certain bias.Regression analysis found that the carotid artery atherosclerosis is closely related to the level of blood pressure,high blood pressure effects on the degree of carotid artery atherosclerosis from light to heavy in order:successful blood pressure control and the duration of<10 years,a successful blood pressure control and the duration of 10 years or more,and blood pressure falls below the duration<10 years,blood pressure control standards and duration of 10 years or more,the carotid intima-media thickness,plaque fo rmationwere more significant with long duration of hypertension and blood pressure control fall,and a successful blood pressure control in a certain extent,correcting the influence of course for atherosclerotic lesions.4 The syndrome factors distributionCompared with Non-hypertension group,Hypertension group mainly performed in Yang deficiency,blood stasis,Yin-yang deficiency,especially in the Yang deficiency and blood stasis;The Non-hypertension group mainly performed in qi deficiency and Yin deficiency,fire higher.By analysis the relationships of Yang deficiency,the general information and risk factors,age and the level of blood pressure control standards was obvious in patients with Yang deficiency.And the higher the blood pressure level classification,the more Yang deficiency performance,blood stasis obvious in the hypertention population.Based on the blood pressure control Yang deficiency,Yin deficiency,phlegm wet differences statistically significant(P<0.05).Yang deficiency,phlegm wet evident of blood pressure target group performance significant,maybe associated with with the risk factors and physical fitness.Conclusions1 Hyperlipidemia,obesity,diabetes in people at high risk of stroke with hypertension were gathered,while associated with hypertension course,with high incidence of carotid atherosclerosis.2 People at high risk of stroke with hypertension mainly performed in Yang deficiency,Qi deficiency and blood stasis,Yin deficiency,blood stasis,qi deficiency,Yin-yang deficiency,fire,and phlegm wet,especially in the Yang deficiency and blood stasis.