Objective: To observe the clinical efficacy and safety of Jiajian Xinyi powder in the treatment of upper airway cough syndrome.Methods: 72 patients with upper airway cough syndrome of wind phlegm invading orifices were randomly divided into control group and treatment group with 36 cases in each group.Both groups were treated for 2 weeks.The TCM syndrome score and cough symptom score table were analyzed and compared before and after treatment.One month after the treatment,the TCM syndrome score evaluation was filled in again to clarify the recurrence.result:1.General data: 69 patients were actually included,35 in the treatment group and 34 in the control group.There was no significant difference in age,gender,course of disease and symptom scores before treatment between the two groups(P > 0.05).2.Treatment effect analysis(1)The results of TCM syndrome score showed that the total effective rate of the treatment group was 94.29% and that of the control group was 76.47%.The comparison of the curative effect evaluation,TCM syndrome score before and after treatment and recurrence evaluation between the two groups showed that the curative effect of the treatment group was better than that of the control group(P < 0.05).The analysis of the comparison results between the two groups showed that all TCM syndrome scores of the two groups after treatment were significantly lower than those before treatment(P < 0.05),and the treatment schemes of the two groups could improve the symptoms of the disease.Comparison between the two groups: the improvement of cough,expectoration,nasal congestion,runny nose and postnasal drip in the treatment group was better than that in the control group(P < 0.05),and there was no significant difference between the two groups in symptoms and signs such as nasal mucosa pallor and edema,pharyngeal itching,posterior pharyngeal wall and tongue root follicles,headache and so on(P > 0.05).(2)Cough symptom score table: after treatment,the treatment group was significantly better than the control group in improving cough symptoms(P < 0.05),indicating that the treatment group was significantly better than the control group in improving cough degree.(3)Recurrence assessmentThere were 7 cases of recurrence in the treatment group and 12 cases in the control group.The recurrence of the two groups was statistically significant(P < 0.05).The recurrence rate in the treatment group was significantly lower than that in the control group.Conclusion:1.the combination of Jiajian Xinyi powder and conventional western medicine has a significant effect on patients with upper airway cough syndrome of wind phlegm invading orifices,which is better than conventional western medicine.It can significantly improve the symptoms of patients and reduce the recurrence of the disease.2.the combination of Jiajian Xinyi powder and conventional western medicine has significant curative effect and drug safety,and has the value of promotion and application in clinical practice. |