Clinical Study On The Treatment Of Senile ILD With The Method Of Invigorating The Lung,Tonifying The Kidney And Activating Blood Circulation

Objective: This topic selected the elderly patients with interstitial lung disease at stable stage(deficiency of lung and kidney and blood stasis type)to be given the self-made prescription of invigorating the lung and kidney and activating blood circulation,and observed the effect of the method of invigorating the lung and kidney and activating blood circulation on the TCM syndrome of the disease,six-minute walking test,the score of the quality of life questionnaire(HRQOL),lung function and other indicators in clinical treatment,so as to clarify the therapeutic role of the self-made prescription of invigorating the lung and kidney and activating blood circulation in the elderly patients with interstitial lung disease,Further deepen the understanding of senile interstitial lung disease,in order to provide ideas for expanding the clinical application of traditional Chinese medicine in senile interstitial lung disease.Content: Through reviewing relevant literature and combining clinical observations of patients,we conducted in-depth exploration of the pathogenesis of elderly patients with interstitial lung disease,and ultimately proposed the research topic of "Clinical Research on the Treatment of Elderly Interstitial Lung Disease with the Method of Tonifying the Lung,Tonifying the Kidney,and Promoting Blood Circulation".This study recruited patients with interstitial lung disease who were over 60 years old and treated at the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,By observing the clinical efficacy and safety of the method of tonifying the lungs,tonifying the kidneys,and promoting blood circulation in patients with interstitial lung disease of lung and kidney deficiency and blood stasis type,and comparing the differences between the combination of traditional Chinese and Western medicine treatment and simple Western medicine treatment,the aim is to better improve the clinical symptoms and exercise endurance of patients,enhance the lung ventilation function of ILD patients,and thereby improve their quality of life.Methods: Select 64 patients who meet the inclusion and exclusion criteria of this study and randomly divide them into an observation group and a control group,with 32 patients in each group.The control group received standardized Western medicine treatment,while the observation group received self formulated prescriptions for tonifying the lungs,tonifying the kidneys,and promoting blood circulation on this basis.The treatment lasted for 12 consecutive weeks,with both groups receiving one treatment course.During the observation period,a total of 4 cases of detachment and exclusion were observed.Observe and record the changes in various observation indicators of the remaining 60 patients,while paying attention to monitoring safety observation indicators.Compare and statistically analyze the data obtained before and after treatment between the two groups of patients.Results: There was no statistical difference between the observation group and the control group before treatment(p>0.05).Compared with the patients in the two groups before and after treatment,the quantized integral of TCM syndrome was significantly reduced(P<0.01);The oxygen saturation(SPO2),six-minute total walking distance(6MWD),lung function test(FVC,FEV1,TLC-SB,DLCO)and seven dimensions of HRQOL(physiological function(PF),physiological function(RP),general health(GH),vitality(VT),social function(SF),emotional function(RE),and mental health(MH))of the six-minute walking test were improved compared with those before treatment(P<0.01),Both treatments had no significant effect on reducing body pain(BP)of HRQOL(P>0.05).After treatment,compared with the other groups,the score reduction of TCM syndrome quantification table in the observation group was more significant(P<0.05);The increase of 6MWD,PF,RP,GH,VT,FVC,TLC-SB and DLCO in the observation group were significantly better than those in the control group(P<0.05);In terms of SPO2,BP,SF,RE,MH and FEV1,there was no significant difference between the two groups(P>0.05).Conclusion: The self-prepared prescription of invigorating the lung,tonifying the kidney and activating blood circulation combined with conventional western medicine can significantly relieve the clinical symptoms of elderly patients with interstitial lung disease,enhance the lung ventilation function of patients with ILD,improve their activity and exercise endurance,delay the progress of the disease,and improve the quality of life,which is a relatively safe treatment method.